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Comment: C: Why can we still be able to continously discover new cancer driver bioinformatic
3.9 years ago by CY ▴ 730
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1
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1.1k
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Comment: C: Why can we still be able to continously discover new cancer driver bioinformatic
3.9 years ago by CY ▴ 730
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1
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2.6k
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Answer: A: Whole Blood Samples of Cancer Patients from TCGA?
updated 3.9 years ago by 40k • written 8.0 years ago by ▴ 730
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0
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10k
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Comment: C: how to use ESTIMATE to infer tumor purity and stromal score from RNA-seq data?
3.9 years ago by CY ▴ 730
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5
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908
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Composition of low mappable region in human genome
mappability repetitive region homologous region
updated 3.9 years ago by 20 • written 4.0 years ago by ▴ 730
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0
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541
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Any absolute quantification method for detection of polyploidy tumor sample
PCR RNA-Seq
4.0 years ago by CY ▴ 730
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0
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7.5k
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Comment: C: What is the best way to combine machine learning algorithms for feature selectio
4.0 years ago by CY ▴ 730
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1
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908
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Comment: C: Composition of low mappable region in human genome
4.0 years ago by CY ▴ 730
0
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1
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908
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Comment: C: Composition of low mappable region in human genome
4.0 years ago by CY ▴ 730
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0
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2.4k
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Comment: C: Regions to exclude in CNV analysis
4.0 years ago by CY ▴ 730
1
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2
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1.1k
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How splice-aware aligner (RNA-Seq) deal with long gap (intron) penalty
RNA-Seq STAR alignment hisat tophat
updated 4.0 years ago by 20 • written 4.0 years ago by ▴ 730
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0
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772
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Comment: C: How does base quality / mapping quality affect germline calling
4.0 years ago by CY ▴ 730
1
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3
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772
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How does base quality / mapping quality affect germline calling
haplotypecaller germline calling MAPQ
4.0 years ago by CY ▴ 730
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1
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2.7k
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Comment: C: Infer somatic mutations without normal control
4.0 years ago by CY ▴ 730
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0
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1.1k
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Comment: C: non-reference allele didn't be called into vcf by HC
4.0 years ago by CY ▴ 730
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0
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5.1k
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Comment: C: "Protein search using Blastp" vs "protein search using hmm profile"
4.0 years ago by CY ▴ 730
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1
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1.1k
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Comment: C: non-reference allele didn't be called into vcf by HC
4.0 years ago by CY ▴ 730
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4
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1.1k
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non-reference allele didn't be called into vcf by HC
haplotypecaller vcf
updated 4.0 years ago by 86k • written 4.0 years ago by ▴ 730
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2
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2.7k
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Comment: C: Infer somatic mutations without normal control
4.0 years ago by CY ▴ 730
0
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1
reply
801
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Dispersion shrinkage in DESeq2: LOESS instead of negative binomial based GLM?
RNA-SEQ DESeq
4.1 years ago by CY ▴ 730
1
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5
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797
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Archieve of homologous nucleotide sequence across genome
sequence
updated 4.1 years ago by ▴ 130 • written 4.1 years ago by ▴ 730
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1
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797
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Comment: C: Archieve of homologous nucleotide sequence across genome
4.1 years ago by CY ▴ 730
0
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0
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899
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XHMM calls CNV on a number of normal samples
CNV XHH
4.1 years ago by CY ▴ 730
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0
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1.4k
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Comment: C: Library size normalization during CNV calling from genomically doubled tumor tis
4.1 years ago by CY ▴ 730
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9
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1.4k
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Library size normalization during CNV calling from genomically doubled tumor tissue
CNV
updated 4.1 years ago by ▴ 550 • written 4.1 years ago by ▴ 730
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1
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1.4k
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Comment: C: Library size normalization during CNV calling from genomically doubled tumor tis
4.1 years ago by CY ▴ 730
1
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0
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1.1k
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Comment: C: Noisy CNV background in old FFPE sample
4.2 years ago by CY ▴ 730
1
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1
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1.1k
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Comment: C: Noisy CNV background in old FFPE sample
4.2 years ago by CY ▴ 730
6
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5
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1.1k
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Noisy CNV background in old FFPE sample
CNV FFPE
updated 4.2 years ago by ★ 2.8k • written 4.2 years ago by ▴ 730
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0
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796
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Comment: C: Effect size in power analysis when dealing with Poisson based variant caller
4.2 years ago by CY ▴ 730
1
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3
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796
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Effect size in power analysis when dealing with Poisson based variant caller
variant calling
updated 4.2 years ago by ▴ 550 • written 4.2 years ago by ▴ 730
0
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0
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992
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Difference between mpileup and HaplotypeCaller -ERC BP_RESOLUTION
variant calling haplotypecaller mpileup
4.2 years ago by CY ▴ 730
3
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7
replies
1.2k
views
Why methylation sequencing requires much less sequencing depth than DNA-Seq?
methylation WGBS
updated 4.3 years ago by 8.2k • written 4.3 years ago by ▴ 730
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1
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1.2k
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Comment: C: Why methylation sequencing requires much less sequencing depth than DNA-Seq?
4.3 years ago by CY ▴ 730
0
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1
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1.2k
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Comment: C: Why methylation sequencing requires much less sequencing depth than DNA-Seq?
4.3 years ago by CY ▴ 730
0
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1
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1.4k
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Comment: C: Why do so many biomarker based classifiers claim high accuracy but rarely used i
4.3 years ago by CY ▴ 730
21
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4
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1.4k
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Why do so many biomarker based classifiers claim high accuracy but rarely used in clinical setting?
biomarker
4.3 years ago by CY ▴ 730
0
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1
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853
views
Mutated gene based pathway enrichment
enrichment mutation
updated 4.3 years ago by ▴ 990 • written 4.3 years ago by ▴ 730
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0
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721
views
Why seed and fuzzy-search in MIGEC?
MIGEC MUI tcr
4.4 years ago by CY ▴ 730
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0
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8.1k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.4 years ago by CY ▴ 730
0
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0
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8.1k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.4 years ago by CY ▴ 730
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2
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8.1k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.4 years ago by CY ▴ 730
0
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1
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8.1k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.4 years ago by CY ▴ 730
0
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1
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8.1k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.4 years ago by CY ▴ 730
0
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0
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8.1k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.4 years ago by CY ▴ 730
27
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17
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8.1k
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Why can't use t-test for differential expression (negative binomial distribution assumed)
RNA-Seq
updated 4.4 years ago by 13k • written 4.4 years ago by ▴ 730
0
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1
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8.1k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.4 years ago by CY ▴ 730
2
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12
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1.8k
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Multiple testing correction issue
multiple testing correction
updated 4.5 years ago by 13k • written 4.5 years ago by ▴ 730
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2
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1.8k
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Comment: C: Multiple testing correction issue
4.5 years ago by CY ▴ 730
0
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0
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1.8k
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Comment: C: Multiple testing correction issue
4.5 years ago by CY ▴ 730
275 results • Page 2 of 6
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