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Comment: C: Why can we still be able to continously discover new cancer driver bioinformatic
3.5 years ago by CY ▴ 720
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1
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2.5k
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Answer: A: Whole Blood Samples of Cancer Patients from TCGA?
updated 3.6 years ago by 39k • written 7.7 years ago by ▴ 720
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0
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9.7k
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Comment: C: how to use ESTIMATE to infer tumor purity and stromal score from RNA-seq data?
3.6 years ago by CY ▴ 720
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0
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423
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Method to detect genome doubling
CNV genome doubling
3.6 years ago by CY ▴ 720
1
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5
replies
809
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Composition of low mappable region in human genome
mappability repetitive region homologous region
updated 3.6 years ago by 20 • written 3.6 years ago by ▴ 720
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0
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488
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Any absolute quantification method for detection of polyploidy tumor sample
PCR RNA-Seq
3.6 years ago by CY ▴ 720
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0
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6.9k
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Comment: C: What is the best way to combine machine learning algorithms for feature selectio
3.6 years ago by CY ▴ 720
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1
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809
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Comment: C: Composition of low mappable region in human genome
3.6 years ago by CY ▴ 720
0
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1
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809
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Comment: C: Composition of low mappable region in human genome
3.6 years ago by CY ▴ 720
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0
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2.3k
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Comment: C: Regions to exclude in CNV analysis
3.6 years ago by CY ▴ 720
1
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2
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988
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How splice-aware aligner (RNA-Seq) deal with long gap (intron) penalty
RNA-Seq STAR alignment hisat tophat
updated 3.7 years ago by 20 • written 3.7 years ago by ▴ 720
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0
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699
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Comment: C: How does base quality / mapping quality affect germline calling
3.7 years ago by CY ▴ 720
1
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3
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699
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How does base quality / mapping quality affect germline calling
haplotypecaller germline calling MAPQ
3.7 years ago by CY ▴ 720
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1
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2.6k
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Comment: C: Infer somatic mutations without normal control
3.7 years ago by CY ▴ 720
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0
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990
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Comment: C: non-reference allele didn't be called into vcf by HC
3.7 years ago by CY ▴ 720
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0
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4.9k
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Comment: C: "Protein search using Blastp" vs "protein search using hmm profile"
3.7 years ago by CY ▴ 720
0
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1
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990
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Comment: C: non-reference allele didn't be called into vcf by HC
3.7 years ago by CY ▴ 720
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4
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990
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non-reference allele didn't be called into vcf by HC
haplotypecaller vcf
updated 3.7 years ago by 85k • written 3.7 years ago by ▴ 720
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2
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2.6k
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Comment: C: Infer somatic mutations without normal control
3.7 years ago by CY ▴ 720
0
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1
reply
742
views
Dispersion shrinkage in DESeq2: LOESS instead of negative binomial based GLM?
RNA-SEQ DESeq
3.8 years ago by CY ▴ 720
1
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5
replies
707
views
Archieve of homologous nucleotide sequence across genome
sequence
updated 3.8 years ago by ▴ 130 • written 3.8 years ago by ▴ 720
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1
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707
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Comment: C: Archieve of homologous nucleotide sequence across genome
3.8 years ago by CY ▴ 720
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0
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851
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XHMM calls CNV on a number of normal samples
CNV XHH
3.8 years ago by CY ▴ 720
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0
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1.2k
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Comment: C: Library size normalization during CNV calling from genomically doubled tumor tis
3.8 years ago by CY ▴ 720
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9
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1.2k
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Library size normalization during CNV calling from genomically doubled tumor tissue
CNV
updated 3.8 years ago by ▴ 550 • written 3.8 years ago by ▴ 720
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1
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1.2k
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Comment: C: Library size normalization during CNV calling from genomically doubled tumor tis
3.8 years ago by CY ▴ 720
1
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0
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961
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Comment: C: Noisy CNV background in old FFPE sample
3.9 years ago by CY ▴ 720
1
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1
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961
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Comment: C: Noisy CNV background in old FFPE sample
3.9 years ago by CY ▴ 720
6
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5
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961
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Noisy CNV background in old FFPE sample
CNV FFPE
updated 3.9 years ago by ★ 2.8k • written 3.9 years ago by ▴ 720
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0
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707
views
Comment: C: Effect size in power analysis when dealing with Poisson based variant caller
3.9 years ago by CY ▴ 720
1
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3
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707
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Effect size in power analysis when dealing with Poisson based variant caller
variant calling
updated 3.9 years ago by ▴ 550 • written 3.9 years ago by ▴ 720
0
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0
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946
views
Difference between mpileup and HaplotypeCaller -ERC BP_RESOLUTION
variant calling haplotypecaller mpileup
3.9 years ago by CY ▴ 720
3
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7
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1.1k
views
Why methylation sequencing requires much less sequencing depth than DNA-Seq?
methylation WGBS
updated 3.9 years ago by 8.2k • written 3.9 years ago by ▴ 720
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1
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1.1k
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Comment: C: Why methylation sequencing requires much less sequencing depth than DNA-Seq?
3.9 years ago by CY ▴ 720
0
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1
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1.1k
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Comment: C: Why methylation sequencing requires much less sequencing depth than DNA-Seq?
3.9 years ago by CY ▴ 720
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1
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1.3k
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Comment: C: Why do so many biomarker based classifiers claim high accuracy but rarely used i
4.0 years ago by CY ▴ 720
21
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4
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1.3k
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Why do so many biomarker based classifiers claim high accuracy but rarely used in clinical setting?
biomarker
4.0 years ago by CY ▴ 720
0
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1
reply
803
views
Mutated gene based pathway enrichment
enrichment mutation
updated 4.0 years ago by ▴ 990 • written 4.0 years ago by ▴ 720
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0
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674
views
Why seed and fuzzy-search in MIGEC?
MIGEC MUI tcr
4.1 years ago by CY ▴ 720
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0
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7.2k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.1 years ago by CY ▴ 720
0
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0
replies
7.2k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.1 years ago by CY ▴ 720
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2
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7.2k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.1 years ago by CY ▴ 720
0
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1
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7.2k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.1 years ago by CY ▴ 720
0
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1
reply
7.2k
views
Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.1 years ago by CY ▴ 720
0
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0
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7.2k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.1 years ago by CY ▴ 720
26
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17
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7.2k
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Why can't use t-test for differential expression (negative binomial distribution assumed)
RNA-Seq
updated 4.1 years ago by 13k • written 4.1 years ago by ▴ 720
0
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1
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7.2k
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Comment: C: Why can't use t-test for differential expression (negative binomial distribution
4.1 years ago by CY ▴ 720
2
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12
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1.6k
views
Multiple testing correction issue
multiple testing correction
updated 4.1 years ago by 13k • written 4.1 years ago by ▴ 720
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2
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1.6k
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Comment: C: Multiple testing correction issue
4.1 years ago by CY ▴ 720
0
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0
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1.6k
views
Comment: C: Multiple testing correction issue
4.1 years ago by CY ▴ 720
275 results • Page 2 of 6
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