User: carlos_marchi

gravatar for carlos_marchi
Reputation:
60
Status:
Trusted
Location:
Brazil, Sorocaba, UFABC
Last seen:
2 weeks, 4 days ago
Joined:
4 years, 1 month ago
Email:
c************@yahoo.com.br

Posts by carlos_marchi

<prev • 28 results • page 1 of 3 • next >
1
vote
1
answer
588
views
1
answers
Comment: C: How to calculate synergy score between two drugs?
... Hi Dwooten, I really appreciate your help. Thank you very much for creating the python package and your explanation. It is not clear for me how to create a drug response dataset that it passed in the fit method. Can you give a link, article that I can understand how to create that dataset? Tha ...
written 19 days ago by carlos_marchi60
0
votes
0
answers
93
views
0
answers
Drug-Drug similarity database
... Hi, I'd like to know if there are biological databases related to drug-drug interactions based on their similaries. I suppose the Stitch db has chemical-chemical interaction. Thank you very much ...
ddi drug drug_similarity written 8 weeks ago by carlos_marchi60
0
votes
1
answer
106
views
1
answer
Is there a level (distance) criteria about protein relationship in the PPI network?
... For example, is there a PPI network where protein P1 is related to P2, P2 with P3. Can I suppose that P1 related to P3 because the relationship between P2 and P3? Is there a criteria about the relationship level between two proteins? In this case, I will use shortest path algorithm to get the dista ...
ppi protein written 3 months ago by carlos_marchi60 • updated 3 months ago by lieven.sterck8.3k
3
votes
1
answer
231
views
1
answer
How to retrieve protein sequence data for humano in UniProt?
... Hi, I tried to retrieve protein sequence data from UniProt site, however, I haven't downloaded the data because is huge files ( about 130GB). I suppose, there are all species in that file. Is there a manner to download just protein sequence data from UniProt specific for human? Thank you ver ...
protein sequence protein uniprot written 11 months ago by carlos_marchi60 • updated 11 months ago by a.zielezinski9.2k
1
vote
1
answer
293
views
1
answer
How to get the list of human domains in the PFAM database?
... Hi, I downloaded the Pfam-A.full in the PFAM database FTP wich contains the entire information about domains. However, I'd like to know whether there is possible two retrive a file with just human domains or get human domains in the Pfam-A.full. Thank you very much ...
human domain pfam written 12 months ago by carlos_marchi60 • updated 12 months ago by h.mon30k
1
vote
1
answer
251
views
1
answers
Answer: A: is there a method two compare EC similarity?
... I found a solution... First, you have to create a matrix with all enzyme classes where each cell corresponds to an enzyme class. You can download the enzyme classes in the Enzyme Database: [enter link description here][1] To compare two EC numbers, you have to convert the EC number to a bit array ...
written 12 months ago by carlos_marchi60
1
vote
1
answer
251
views
1
answer
is there a method two compare EC similarity?
... Hi there, Given two proteins with their EC Numbers, I'd like to know if the EC number are similarity. Is there a method, web service or python implementation for calculate ec similarity? Thank you very much ...
ecc number drug enzyme written 12 months ago by carlos_marchi60
0
votes
1
answer
471
views
1
answers
Comment: C: Which should items consider to creste a dru-drug-gene interaction network?
... Hi dselleno! That's my email: carlos_marchi@yahoo.com.br Thank you very much! ...
written 13 months ago by carlos_marchi60
3
votes
1
answer
588
views
1
answer
How to calculate synergy score between two drugs?
... Hi, I'm curious about the calculation of drug synergy, I'm novice in these field. I would like to know how to calculate the synergy score between two drugs using one of these methods: Loewe Additivity, Highest Single Agent, Response Additivity, Bliss Independence or ZIP. Is there any implementation ...
drug drug synergy combination index written 14 months ago by carlos_marchi60 • updated 17 days ago by dwooten10
0
votes
1
answer
360
views
1
answers
Comment: C: Which are the protein classes
... Olá Kevin! Eu vi no site do drugbank uma classificação de proteínas alvos de drogas, podendo ser Target, Enzyme, Carrie e Transporter. Em alguns artigos que li, eles utilizaram alvos de drogas relacionadas a GPRC, Transcriptor Factor, Nuclear receptor, dentre outros. Gostaria de saber se há uma list ...
written 14 months ago by carlos_marchi60

Latest awards to carlos_marchi

Popular Question 10 months ago, created a question with more than 1,000 views. For Doubts about TCGA DNA Methylation samples
Scholar 11 months ago, created an answer that has been accepted. For A: Data integration between gene expression - RNAseq and DNA methylation - Illumina
Popular Question 17 months ago, created a question with more than 1,000 views. For Data integration between gene expression - RNAseq and DNA methylation - Illumina 450k
Popular Question 3.8 years ago, created a question with more than 1,000 views. For Data integration between gene expression - RNAseq and DNA methylation - Illumina 450k
Popular Question 3.8 years ago, created a question with more than 1,000 views. For Doubts about TCGA DNA Methylation samples
Popular Question 3.8 years ago, created a question with more than 1,000 views. For get correlation matrix from principal component analysis in python
Scholar 4.0 years ago, created an answer that has been accepted. For A: Data integration between gene expression - RNAseq and DNA methylation - Illumina
Scholar 4.1 years ago, created an answer that has been accepted. For A: Data integration between gene expression - RNAseq and DNA methylation - Illumina

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1127 users visited in the last hour