User: carlos_marchi

gravatar for carlos_marchi
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60
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Brazil, São Paulo
Last seen:
6 days, 14 hours ago
Joined:
4 years, 5 months ago
Email:
c************@yahoo.com.br

Posts by carlos_marchi

<prev • 30 results • page 1 of 3 • next >
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R or python packages for differential methylation levels analysis: case x control
... Hi, There are several txt files in which each corresponds to a patient containing measure methylation levels in both conditionals: case and control. Filename corresponds to patient identification and inside the file contains three columns: gene symbol, case and control. The DNA methylation levels c ...
python humanmethylation450 dnamthylation R written 7 days ago by carlos_marchi60
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How to generate dose-response matrices for drug pairs?
... Hi, I would like to know how to create a dose-response matrix for a drug pair. I'd like to know what criteria is related to dosage values for each drugs, for example the dosage quantity items for each drug, minimum and maximum dosage for each drug, mL type dosage and ec50. Furthermore, how to calc ...
drug-combination drug-effect drug written 8 weeks ago by carlos_marchi60
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Comment: C: How to calculate synergy score between two drugs?
... Hi Dwooten, I really appreciate your help. Thank you very much for creating the python package and your explanation. It is not clear for me how to create a drug response dataset that it passed in the fit method. Can you give a link, article that I can understand how to create that dataset? Tha ...
written 4 months ago by carlos_marchi60
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Drug-Drug similarity database
... Hi, I'd like to know if there are biological databases related to drug-drug interactions based on their similaries. I suppose the Stitch db has chemical-chemical interaction. Thank you very much ...
ddi drug drug_similarity written 5 months ago by carlos_marchi60
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Is there a level (distance) criteria about protein relationship in the PPI network?
... For example, is there a PPI network where protein P1 is related to P2, P2 with P3. Can I suppose that P1 related to P3 because the relationship between P2 and P3? Is there a criteria about the relationship level between two proteins? In this case, I will use shortest path algorithm to get the dista ...
ppi protein written 6 months ago by carlos_marchi60 • updated 6 months ago by lieven.sterck8.9k
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How to retrieve protein sequence data for humano in UniProt?
... Hi, I tried to retrieve protein sequence data from UniProt site, however, I haven't downloaded the data because is huge files ( about 130GB). I suppose, there are all species in that file. Is there a manner to download just protein sequence data from UniProt specific for human? Thank you ver ...
protein sequence protein uniprot written 15 months ago by carlos_marchi60 • updated 15 months ago by a.zielezinski9.3k
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How to get the list of human domains in the PFAM database?
... Hi, I downloaded the Pfam-A.full in the PFAM database FTP wich contains the entire information about domains. However, I'd like to know whether there is possible two retrive a file with just human domains or get human domains in the Pfam-A.full. Thank you very much ...
human domain pfam written 15 months ago by carlos_marchi60 • updated 15 months ago by h.mon31k
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Answer: A: is there a method two compare EC similarity?
... I found a solution... First, you have to create a matrix with all enzyme classes where each cell corresponds to an enzyme class. You can download the enzyme classes in the Enzyme Database: [enter link description here][1] To compare two EC numbers, you have to convert the EC number to a bit array ...
written 15 months ago by carlos_marchi60
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is there a method two compare EC similarity?
... Hi there, Given two proteins with their EC Numbers, I'd like to know if the EC number are similarity. Is there a method, web service or python implementation for calculate ec similarity? Thank you very much ...
ecc number drug enzyme written 15 months ago by carlos_marchi60
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Comment: C: Which should items consider to creste a dru-drug-gene interaction network?
... Hi dselleno! That's my email: carlos_marchi@yahoo.com.br Thank you very much! ...
written 16 months ago by carlos_marchi60

Latest awards to carlos_marchi

Popular Question 13 months ago, created a question with more than 1,000 views. For Doubts about TCGA DNA Methylation samples
Scholar 15 months ago, created an answer that has been accepted. For A: Data integration between gene expression - RNAseq and DNA methylation - Illumina
Popular Question 20 months ago, created a question with more than 1,000 views. For Data integration between gene expression - RNAseq and DNA methylation - Illumina 450k
Popular Question 4.1 years ago, created a question with more than 1,000 views. For Data integration between gene expression - RNAseq and DNA methylation - Illumina 450k
Popular Question 4.1 years ago, created a question with more than 1,000 views. For Doubts about TCGA DNA Methylation samples
Popular Question 4.1 years ago, created a question with more than 1,000 views. For get correlation matrix from principal component analysis in python
Scholar 4.3 years ago, created an answer that has been accepted. For A: Data integration between gene expression - RNAseq and DNA methylation - Illumina
Scholar 4.4 years ago, created an answer that has been accepted. For A: Data integration between gene expression - RNAseq and DNA methylation - Illumina

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