User: carlos_marchi

gravatar for carlos_marchi
Reputation:
40
Status:
New User
Location:
Brazil, Sorocaba, UFABC
Last seen:
5 days, 8 hours ago
Joined:
2 years, 12 months ago
Email:
c************@yahoo.com.br

Posts by carlos_marchi

<prev • 20 results • page 1 of 2 • next >
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How to calculate synergy score between two drugs?
... Hi, I'm curious about the calculation of drug synergy, I'm novice in these field. I would like to know how to calculate the synergy score between two drugs using one of these methods: Loewe Additivity, Highest Single Agent, Response Additivity, Bliss Independence or ZIP. Is there any implementation ...
drug drug synergy combination index written 9 days ago by carlos_marchi40
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Comment: C: Which are the protein classes
... Olá Kevin! Eu vi no site do drugbank uma classificação de proteínas alvos de drogas, podendo ser Target, Enzyme, Carrie e Transporter. Em alguns artigos que li, eles utilizaram alvos de drogas relacionadas a GPRC, Transcriptor Factor, Nuclear receptor, dentre outros. Gostaria de saber se há uma list ...
written 23 days ago by carlos_marchi40
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Comment: C: Which are the protein classes
... Hi Kevin! In fact, I'd like to know if there is a functional classification of proteins that is used in any biological protein databases. For example, DrugBank uses 4 classes of drug targets: Enzymes, Transporters, Carries and Receptors. However, I read in some articles using other classes, includin ...
written 23 days ago by carlos_marchi40
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Which are the protein classes
... Hi, I'd like to know if there is a list of universal protein classes and there is a protein database in which each one has its corresponding protein class. I haven't found this classification in Uniprot database, for example. Here is an example of protein classes that I find: https://www.proteina ...
proteome database protein written 26 days ago by carlos_marchi40 • updated 18 days ago by Elisabeth Gasteiger1.6k
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Which should items consider to creste a dru-drug-gene interaction network?
... Hi, Assuming there is a list of human genes. I would like to know what to consider creating a drug-drug interaction network where only drug selected based on their correspondence to the gene target. Furthermore, what to consider in the relationships among the nodes (drugs) in the Network? Would i ...
ddg network drug written 3 months ago by carlos_marchi40
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Is there a metabolites human database that contains preprocessing data?
... Hi! I'd like to know whether there is a metabolites human database that contains preprocessing metabolite profiling envolving control and case conditions? Does HMDB contains preprocessing metabolite profiling? Thank you very much! Carlos ...
metabolics written 3 months ago by carlos_marchi40
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Is there Patient's samples in the Lipidomics database
... Hi! Os there a public lipidomics database that contains patient's samples? Thank you very much! ...
lipidomics database written 4 months ago by carlos_marchi40
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Comment: C: get correlation matrix from principal component analysis in python
... I'd like to generate a gene network correlation. I've already applied spearman and pearson correlation in the dataset, I may apply fisher correlation, however I didn't find any python implementation for it. ...
written 2.8 years ago by carlos_marchi40
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Comment: C: get correlation matrix from principal component analysis in python
... I don't know if it is possible... Is there another algorithm to calculate correlation instead of spearman and pearson correlations where result in a correlation matrix? ...
written 2.8 years ago by carlos_marchi40
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Comment: C: get correlation matrix from principal component analysis in python
... My dataset has values about the differential gene expression. So, each column corresponds a specific gene and rows are the samples. I already applied pearson and spearman correlation, but I'd like to apply pca and get the correlation. ...
written 2.8 years ago by carlos_marchi40

Latest awards to carlos_marchi

Popular Question 2.6 years ago, created a question with more than 1,000 views. For Data integration between gene expression - RNAseq and DNA methylation - Illumina 450k
Popular Question 2.6 years ago, created a question with more than 1,000 views. For Doubts about TCGA DNA Methylation samples
Popular Question 2.6 years ago, created a question with more than 1,000 views. For get correlation matrix from principal component analysis in python
Scholar 2.9 years ago, created an answer that has been accepted. For A: Data integration between gene expression - RNAseq and DNA methylation - Illumina
Scholar 3.0 years ago, created an answer that has been accepted. For A: Data integration between gene expression - RNAseq and DNA methylation - Illumina

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