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questions
0
votes
0
replies
313
views
How Can I Identify Genes in the Top 100 Rank Space from SVD?
Singular-Value-Decomposition
Dimension-Reduction
SVD
updated 7 months ago by
Ram
43k • written 7 months ago by
Raheleh
▴ 260
2
votes
5
replies
969
views
How to construct an adjacency matrix based on output of nearest neighbors search method from RANN package?
igraph
RANN
adjacency-matrix
updated 7 months ago by
bk11
★ 2.3k • written 7 months ago by
Raheleh
▴ 260
0
votes
0
replies
377
views
how to ensure that embedding for the new data is initialized based on the embedding of the existing data in UMAP?
UMAP
10 months ago by
Raheleh
▴ 260
0
votes
4
replies
902
views
How to resolve this Error in checkFullRank(modelMatrix) in DESeq2 ?
Batch
correction
DESeq2
RNAseq
updated 2.1 years ago by
andrew.j.skelton73
6.5k • written 2.1 years ago by
Raheleh
▴ 260
4
votes
8
replies
1.9k
views
how to get ride of duplicated genes when we also have duplicated Ensemble ID in the expression profile?
RNA-Seq
duplicated ENSEMBLE ID
collapseRows
updated 2.5 years ago by
fana
▴ 40 • written 3.6 years ago by
Raheleh
▴ 260
1
vote
1
reply
620
views
problem with contrastive principal component analysis (cPCA)
scPCA
cPCA
updated 2.9 years ago by
ATpoint
81k • written 2.9 years ago by
Raheleh
▴ 260
0
votes
0
replies
850
views
How RNAseq input file for ssGSAE should be normalized?
VST
ssGSEA
normalization
2.8 years ago by
Raheleh
▴ 260
2
votes
1
reply
794
views
Why the result of GSEA and ssGSEA is different?
ssgsea
gsea
updated 9 months ago by
evertzz
• 0 • written 3.1 years ago by
Raheleh
▴ 260
0
votes
0
replies
669
views
How to do differential CNA analysis?
CNA
GISTIC
Differential analysis
3.2 years ago by
Raheleh
▴ 260
0
votes
0
replies
590
views
Normalizing multiple conditons all together
RMA
microarray
time-series
updated 10 months ago by
Ram
43k • written 3.5 years ago by
Raheleh
▴ 260
7
votes
7
replies
1.6k
views
Finding a gene signature among multiple group
SAM
RNAseq
signature
updated 17 months ago by
1769mkc
★ 1.2k • written 3.6 years ago by
Raheleh
▴ 260
5
votes
9
replies
1.3k
views
Batch correction using DESeq2
RNA-Seq
deseq2
batch
vst
3.8 years ago by
Raheleh
▴ 260
0
votes
1
reply
1.0k
views
Why some genes with negative fold change are assigned as activated upstream regulators by IPA?
IPA
Upstream regulator
activation z-score
4.0 years ago by
Raheleh
▴ 260
24
votes
16
replies
7.2k
views
Only doing log2 transformation for RNAseq read count data without normalizing by DESeq2 ??!
RNA-Seq
readcount
deseq2
log2
updated 4.1 years ago by
ATpoint
81k • written 4.1 years ago by
Raheleh
▴ 260
10
votes
6
replies
2.2k
views
Why Wilcox.test keep giving (p-val = 0.1) even when there is significant difference between the data?
wilcox.test
ssGSEA
significant level
ggplot
updated 4.2 years ago by
Constantine
▴ 290 • written 4.2 years ago by
Raheleh
▴ 260
2
votes
14
replies
2.2k
views
how to plot lollipop in which dots show mean/median for each variable?
lollipop plot
ggplot2
updated 4.2 years ago by
Asaf
10k • written 4.2 years ago by
Raheleh
▴ 260
1
vote
3
replies
2.6k
views
What should be reported as Hazard Ratio in Kaplan Meier curve?
survival
Hazard Ratio
kaplan meier
updated 4.2 years ago by
discombobulated
▴ 10 • written 4.3 years ago by
Raheleh
▴ 260
0
votes
0
replies
880
views
Prediction Analysis for Microarrays (PAM) method can be used for RNAseq data?
PAMR
RNAseq
prediction
4.3 years ago by
Raheleh
▴ 260
1
vote
4
replies
844
views
Best statistical test to compare the performance of small classifiers?
Statistical test
classifier
Fisher's exact test
updated 4.3 years ago by
Kevin Blighe
87k • written 4.3 years ago by
Raheleh
▴ 260
2
votes
1
reply
784
views
Pathway enrichment analysis for a small set of genes
GSEA
gene signature
pathway enrichment analysis
updated 4.4 years ago by
dsull
★ 5.8k • written 4.4 years ago by
Raheleh
▴ 260
4
votes
4
replies
7.7k
views
How to add Hazard ratio value into Kaplan Meier plot?
kaplan meier
Hazard Ratio
r
ggsurvplot
4.4 years ago by
Raheleh
▴ 260
0
votes
2
replies
1.3k
views
Problem with UpSetR result
UpSetR
Intersections
upset
updated 4.4 years ago by
russhh
5.7k • written 4.4 years ago by
Raheleh
▴ 260
9
votes
8
replies
9.5k
views
How to plot GSEA result?
GSEA plot
fgsea
r
plotEnrichment
updated 4.4 years ago by
Barry Digby
★ 1.3k • written 4.4 years ago by
Raheleh
▴ 260
2
votes
5
replies
1.1k
views
How to identify best predictors in lasso-penalised model?
lasso-penalised
Coefficient
predictor
updated 4.6 years ago by
Jean-Karim Heriche
27k • written 4.6 years ago by
Raheleh
▴ 260
4
votes
7
replies
1.2k
views
huge difference of expression value of different probes for the same gene. Why?
Probe ID of the same gene
updated 4.6 years ago by
ATpoint
81k • written 4.6 years ago by
Raheleh
▴ 260
9
votes
20
replies
4.0k
views
Should the expression data be centered before PCA?
PCA
Centering
expression data
4.7 years ago by
Raheleh
▴ 260
1
vote
1
reply
3.1k
views
how to use custom cdf in R to convert affyID to gene symbol?
affymetrix microarray
custom cdf
gene symbol
updated 4.9 years ago by
Kevin Blighe
87k • written 7.4 years ago by
Raheleh
▴ 260
3
votes
4
replies
4.1k
views
Downstream analysis of VCF files obtained from VarScan2
WES
VCF
Somatic variations
VarScan2
SnpEff
updated 5.0 years ago by
bari.ballew
▴ 460 • written 5.4 years ago by
Raheleh
▴ 260
2
votes
3
replies
3.6k
views
Calling CNV using bcftools
bcftools
CNV
vcf
updated 2.5 years ago by
Waly
• 0 • written 5.2 years ago by
Raheleh
▴ 260
4
votes
9
replies
4.8k
views
Problem in converting vcf to maf using vcf2maf tools
vcf2maf
GRCh38
varscan
5.2 years ago by
Raheleh
▴ 260
2
votes
3
replies
1.3k
views
How to annotate Copy Number Variations (Output of VarScan2)
CNV
VarScan
annotation
updated 5.2 years ago by
Pierre Lindenbaum
161k • written 5.2 years ago by
Raheleh
▴ 260
2
votes
1
reply
3.0k
views
Problem in installing mclust package R
R
mclust
lgfortran
updated 5.3 years ago by
Jean-Karim Heriche
27k • written 5.3 years ago by
Raheleh
▴ 260
0
votes
2
replies
2.0k
views
Problem in using VarScan fpfilter
bam-readcount
varscan fpfilter
snp calling
updated 5.3 years ago by
Biostar
20 • written 5.4 years ago by
Raheleh
▴ 260
8
votes
13
replies
7.9k
views
Problem in using picard.jar
picard
updated 5.4 years ago by
Pierre Lindenbaum
161k • written 5.4 years ago by
Raheleh
▴ 260
7
votes
7
replies
3.2k
views
How to merge vcf files (output of VarScan2 somatic)?
varscan2
merge
vcf
SNP
indel
5.4 years ago by
Raheleh
▴ 260
7
votes
7
replies
3.0k
views
Is it necessary to mark the duplicates, realign the data and recalibrate base quality score (VarScan2)?
VarScan2
WES data
duplicate
realignment
updated 5.4 years ago by
ATpoint
81k • written 5.4 years ago by
Raheleh
▴ 260
0
votes
3
replies
1.3k
views
Problem in generating hc.readcount files using bam-readcount
bam-readcount
hc.readcount file
BAM index
updated 5.4 years ago by
ATpoint
81k • written 5.4 years ago by
Raheleh
▴ 260
0
votes
0
replies
1.3k
views
Error in normalizing lines of sequence in a fasta file using NormalizeFasta (Picard)
picard
NormalizeFasta
varscan
bam-readcount
5.4 years ago by
Raheleh
▴ 260
0
votes
2
replies
1.1k
views
linux command line for analyzing WES data
WES data
linux command line
5.4 years ago by
Raheleh
▴ 260
1
vote
3
replies
1.5k
views
Finding somatic and germline variations in tumor samples with matched ones (paired-end, illumina)
WES data
mpileup file
varscan
updated 5.5 years ago by
ATpoint
81k • written 5.5 years ago by
Raheleh
▴ 260
4
votes
3
replies
2.2k
views
The result of differential gene expression analysis should be extracted based on adj.p.value ?
limma
microarray
bioconductor
R
updated 6 days ago by
Ram
43k • written 6.3 years ago by
Raheleh
▴ 260
13
votes
7
replies
6.6k
views
Why some probes have "NA" for gene symbol and Entrez ID?
affymetrix microarray
NA
genesymbol
updated 7.4 years ago by
Biostar
20 • written 7.4 years ago by
Raheleh
▴ 260
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