User: justinms

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justinms10
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Posts by justinms

<prev • 12 results • page 1 of 2 • next >
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Comment: C: Detecting Homozygous Insertion from Sanger Seq
... Correct. But this is a homozygous insertion and there would only be one peak at this site. I need to confirm that both alleles have the insertion ...
written 10 months ago by justinms10
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Detecting Homozygous Insertion from Sanger Seq
... I have a patient with a homozygous insertion, although I can detect the presence of the insertion using the software that I have, it is not so clear as to whether or not the individual is homozygous for this insertion. Is there any way this can be detected using sanger data? ...
indel sanger written 10 months ago by justinms10 • updated 10 months ago by trausch1.3k
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Modeling Transcription Factor-DNA binding
... I know there are probabilistic models used to determine whether or not a Transcription factor will bind a given DNA sequence but I would like to know given a particular protein sequence the strength or the binding affinity to which it binds its consensus sequence. Are there any algorithms or program ...
transcription factor probabilistic models written 11 months ago by justinms10
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Comment: C: Bioinformatics and Functional Genomics - Jonathan Pevsner
... Well I recently reached Chapter3 in his book on pair wise alignment of sequences and he goes on to explain the several steps of creating Margaret Dayhoff PAM matrices. I try to use his formulas to reconstruct the matrices and I just seem to get lost every time. He doesn't necessarily go into the mat ...
written 11 months ago by justinms10
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Bioinformatics and Functional Genomics - Jonathan Pevsner
... I have recently started this book "Bioinformatics and Functional Genomics" by Jonathan Pevsner which has really inspired myself to dive deeper into bioinformatics and become more familiar with the subject. However, my background is in biology not computational sciences although I have worked in a ge ...
math jonathan pevsner pevsner genomics written 11 months ago by justinms10 • updated 9 months ago by Biostar ♦♦ 20
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Comment: C: Genome Browser and Custom Tracks
... This looks nice actually, how exactly did you extract that information from ExAC? ...
written 2.3 years ago by justinms10
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Genome Browser and Custom Tracks
... Bio Guys, Does anyone know how to display variant information on the genome browser that displays variant frequency as one would visualize in a lolliplot or manhattan plot? ...
genome browser custom track written 2.3 years ago by justinms10
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Comment: C: Visualize Mutation Frequency
... Wow. This tool is amazing. Love it! ...
written 2.3 years ago by justinms10
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Comment: C: Visualize Mutation Frequency
... Thanks! Will be developing my programming skills as soon as possible ...
written 2.3 years ago by justinms10
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Comment: C: Visualize Mutation Frequency
... I am actually quite new to bioinformatics. I believe I will have to first familiarize myself with R? ...
written 2.3 years ago by justinms10

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