User: chrisbala10

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chrisbala1010
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Posts by chrisbala10

<prev • 6 results • page 1 of 1 • next >
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Answer: A: Multiple hypothesis testing, Fst outliers
... Thanks Zev, That is helpful, and we'll play around with the different workflows. Just to clarify further/get your opinion: What would you suggest for identifying "outliers"? It seems like in your Science paper (pigeons), you estimated Fst, and just highlighted the top 1% (seems reasonable). But wi ...
written 24 months ago by chrisbala1010
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Multiple hypothesis testing, Fst outliers
... Hi All, We are trying to identify fst outliers from a comparison of two populations. We've settled on using pFst from the GPAT++ package. To my reading, in such studies folks sometimes use bonferonni or benjami-hochberg-corrected p values. In other cases, I've seen arbitrary cutoffs like 10-8. I' ...
fdr population genomics gpat pfst fst written 2.0 years ago by chrisbala1010
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Comment: C: ABYSS kmer coverage
... thanks... now I know... on to other forms of assembly trouble-shooting! ...
written 2.2 years ago by chrisbala1010
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Comment: C: ABYSS kmer coverage
... Ok, here is the full plot. Is this really normal? This is from ~ 1 lane of PE of a bird genome. R isn't labelling my X axis at the moment, sorry.. ![kmer coverage][1] [1]: http://i.imgur.com/yWepZwa.png ...
written 2.2 years ago by chrisbala1010
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Comment: C: ABYSS kmer coverage
... oops, messed up plotting, one second... ...
written 2.2 years ago by chrisbala1010
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ABYSS kmer coverage
... First post to biostars... hope i do this right.. Hi All, I've been fighting a bit with a an attempt at a genome assembly. Based on reading this forum, I suspect there is an issue with the raw data, but I just want to make sure I've understood everything. Fastqc looks ok. There are some over-repre ...
genome assembly written 2.2 years ago by chrisbala1010

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