User: smt8n

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smt8n0
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Posts by smt8n

<prev • 4 results • page 1 of 1 • next >
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poisson - negative binomial mixture with flexmix and countreg
... Dear all, I am testing making a finite mixture model for poisson and negative binomial on some artificial data using flexmix and countreg packages. Here is the core part of my small script: require("countreg") require("flexmix") ## generating data ## poisson lambda <- 20; n ...
countreg flexmix finite mixture model written 7 months ago by smt8n0
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Answer: A: Differential expression with MAST using scran-normalized data
... Charles, thank you for the answer. At this point, I think that since the whole assumption of the package authors, as they state in the whitepaper, is that "CDR is a proxy for unobserved nuisance factors that should be explicitly modeled", the "cngeneson" factor should be kept there. It was not quite ...
written 14 months ago by smt8n0
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Differential expression with MAST using scran-normalized data
... Hi, I am trying to get DE genes from a scRNA-seq using MAST. The data I am supplying were normalized using scran package. In the MAST vignette, as well as in a separate tutorial, they get a scaling matrix for column sums before running regression and use it as another regression variable, besides t ...
scrna-seq mast scran written 14 months ago by smt8n0
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using limma for analyzing RPPA
... Dear all, We got RPPA data (~300 proteins) from a company and I wanted to extract proteins significantly different from the control. We got data already normalized and just needed to extract "differentially expressed" entities, get p-values, etc. Without having a second thought, I used limma, as I ...
rppa limma differential expression written 23 months ago by smt8n0

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