User: Baylie_321

gravatar for Baylie_321
Baylie_32120
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Location:
London
Last seen:
2 months, 2 weeks ago
Joined:
2 years, 1 month ago
Email:
r**********@hotmail.co.uk

Phd Student in functional genomics and bioinformatics. Keen to learn science!

Posts by Baylie_321

<prev • 20 results • page 1 of 2 • next >
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Comment: C: RRBS Methylation integration with RNA-seq differential expression
... But the differential methylation of just one CpG can surely alter the gene expression? It doesn’t have to be the methylation of the promoter as a whole? See - https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-5387-1 ...
written 4 months ago by Baylie_32120
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RRBS Methylation integration with RNA-seq differential expression
... Hi, I am integrating two data sets - gene expression and rrbs methylation from the same samples on a non-model animal - therefore promoters etc... not very well defined. I have group A I am comparing to B. I have my list of (i) differentially expressed genes and (ii) genes associated with different ...
gene expresison methylation rrbs rna-seq written 4 months ago by Baylie_32120
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Comment: C: WGCNA gene significance
... Hi, I already know how I to do the GO enrichment part, I was seeking opinions on which WGCNA gene list made more sense to pass to my GO enrichment. Many thanks, B ...
written 9 months ago by Baylie_32120
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Comment: A: WGCNA gene significance
... Many thanks for your reply, but I don't think this software is appropriate as I am working on a non-model organism and many of the genes do not have a gene-symbol annotation compatible with the human-gene-symbol. I already carried out DE analysis, and this is in addition to that. ...
written 9 months ago by Baylie_32120
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WGCNA gene significance
... Hi, I have used WGCNA to find gene modules relating to two traits - I see that many people have carried out functional analysis (KEGG/GO) on the modules - does it make more sense to carry out such enrichments on those genes with high significance (p<0.05) rather than on the module as a whole? I ...
gene wgcna rna-seq written 9 months ago by Baylie_32120
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Comment: C: Cox Hazard In R, should pass treatments to the model as a factor?
... Thank you so much for all your help! :) this is much clearer now! ...
written 12 months ago by Baylie_32120
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Comment: A: Cox Hazard In R, should pass treatments to the model as a factor?
... Cheers! Okay, hopefully I am correct in interpreting your answer as: If its set as data$SurvObj <- with(data, Surv(hour, mo == 1)) A hazard ratio of 0.7 for temperature grouping as simply 1,2,3 would be with increasing group number, chance of death (1) over censoring (0) decreases from 1 --> ...
written 12 months ago by Baylie_32120
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Cox Hazard In R, should pass treatments to the model as a factor?
... Hiya, I am looking at using Cox Hazard in R using survivor, I have either (mo) 1=died, 0=censored, time in hours (hour), the temperature treatment (temp_c, 3 groups), condition factor (CF, continuous var). I am confused about handling the temperature group variable and have trialled 2 methods: ...
R survivor cox hazard written 12 months ago by Baylie_32120 • updated 12 months ago by zx87548.7k
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Comment: C: Total CpG genome count
... Yes I have used emboss to predict CpG islands - now I want all CpGs not just islands ...
written 17 months ago by Baylie_32120
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Comment: C: Total CpG genome count
... Yes I have used emboss to predict CpG islands - now I want all CpGs not just islands ...
written 17 months ago by Baylie_32120

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