User: lffu_0032

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lffu_003260
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Posts by lffu_0032

<prev • 34 results • page 2 of 4 • next >
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copy number became inaccurate when downsampling different number fastq reads from a whole fastq file
... Hi, everyone: Recent i am doing CNV analysis, i find a strange thing: 1.when using whole data (after removed dup, for tumor and its control), the copy number value is accurate; 2.but when downsample different fq reads from the whole fq for a certain sample (I just downsample the tumor's fq, and ...
copy number not accurate fastq downsample cnv written 8 months ago by lffu_003260
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Answer: A: Have you ever obtained user guide of ExomeCNV?
... can not find user guide... ...
written 9 months ago by lffu_003260
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Comment: C: estimate tumor purity from target capture sequencing
... thank you. i see that the facet is suit for tumor-normal pair calling, but i have only tumor-only capture data... ...
written 10 months ago by lffu_003260
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estimate tumor purity from capture panel data using tumor-only mode
... Hi, everyone, i have a question: i want to call CNV from FFPE tumor using capture panel data, I need to estimate the tumor purity to adjust the copy number, i only have tumor-only data, is there any public tools or method to do this job? many thanks here. ...
ffpe tumor purity target capture copy number written 10 months ago by lffu_003260 • updated 10 months ago by markus.riester500
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Comment: C: How to detect CNV with panel sequencing?
... For germline cnv calling by using capture panel data, i recommend CoNVaDING ...
written 10 months ago by lffu_003260
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estimate tumor purity from target capture sequencing
... hi, everyone, is there a good way to estimate the tumor purity from target capture sequencing?i need to calculate the copy number and without the purity, the CN may be not accurate. thanks for your kind help. ...
purity tumor target capture sequencing estimation written 14 months ago by lffu_003260 • updated 14 months ago by dariober11k
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Answer: A: Identifying CNVs from targeted amplicon sequencing
... you can try CONVector, it is designed for germinal CNV detection in the PCR-enriched targeted sequencing data. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075217/pdf/12859_2016_Article_1272.pdf ...
written 15 months ago by lffu_003260
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Answer: A: amplicon based germline CNV caller
... you can try CONVector, it is designed for germinal CNV detection in the PCR-enriched targeted sequencing data. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075217/pdf/12859_2016_Article_1272.pdf ...
written 15 months ago by lffu_003260
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Comment: C: How to detect CNV with panel sequencing?
... for panel sequencing, how to adjust the XHMM parameters properly?and why "2 for mean number of targets in CNV" is high sensitivity for XHMM? ...
written 16 months ago by lffu_003260
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Comment: C: How to detect CNV with panel sequencing?
... can you give more details about the algorithms in CC2? ...
written 16 months ago by lffu_003260

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