User: jane.merlevede

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Posts by jane.merlevede

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Comment: C: Cleaning the expression matrix for the purpose of deconvolution of RNA-Seq data
... Sorry, I just saw your answer. Yes I mean identification of cell populations in bulk by tumor deconvolution. Using pure cell populations is an interesting approach, used in supervised methods, as CIBERSORT, EPIC, xCell, ... on gene expression data. I assume that when using supervised approaches, th ...
written 17 days ago by jane.merlevede10
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Comment: A: Cleaning the expression matrix for the purpose of deconvolution of RNA-Seq data
... Sorry, I just saw your answer. Yes I mean identification of cell populations in bulk by tumor deconvolution. Using pure cell populations is an interesting approach, used in supervised methods, as CIBERSORT, EPIC, xCell, ... on gene expression data. I assume that when using supervised approaches, th ...
written 17 days ago by jane.merlevede10
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Comment: C: Cleaning the expression matrix for the purpose of deconvolution of RNA-Seq data
... Hello Kevin, Thank you for your answer. I agree with you, for DEA in RNA-Seq, the preprocessing consisting in the suppression of lowly expressed genes only seems now a gold standard and adapted to the normalization step that follows. My concern is rather why a person would perform preprocessing o ...
written 26 days ago by jane.merlevede10
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Job: Postdoc position in development of computational methods for multiscale modeling at Institut Curie (Paris)
... **Post doc position at Institut Curie (Paris) in Computational Systems Biology Group** ------------------------------------------------------------------------ Development of computational methods for multiscale modeling of tumor microenvironment ---------------------------------------------------- ...
modeling job software development written 29 days ago by jane.merlevede10
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Job: Postdoc position in machine learning and statistical analysis of multi-level cancer omics data at Institut Curie (Paris)
... **Postdoc position at Institut Curie (Paris) in Computational Systems Biology Group** ------------------------------------------------------------------------ Machine learning and statistical analysis of multi-level cancer omics data ---------- **Duration:** 18-36 months with possibility of extens ...
computational biology job statistics written 29 days ago by jane.merlevede10
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Job: Postdoc position in computational analysis for single cell molecular data at Institut Curie (Paris)
... **Postdoc position at Institut Curie (Paris) in Systems Biology Group** --------------------------------------------------------------- Computational analysis and method development for single cell molecular data in cancer biology -------------------------------------------------------------------- ...
job single cell computational biology written 29 days ago by jane.merlevede10
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Cleaning the expression matrix for the purpose of deconvolution of RNA-Seq data
... Dear all, I wonder about the cleaning of rna-seq counts in the context of tumor deconvolution based on rna-seq data. When performing classic rna-seq differential expression analysis, it is common to remove the genes that are not and almost not expressed across the samples, leading to the removal o ...
deconvolution preprocessing rna-seq written 29 days ago by jane.merlevede10

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