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Posts by Chiara.Caprioli
... Thanks! the "shallow" coverage of the tumor sample is fine for me, in the context of my project. For general interest, I share this http://dx.doi.org/10.1016/j.jmoldx.2017.01.011 ...
... Hi, I'm performing WES on tumor/germline DNA couples to score driver cancer mutations, using ~200x coverage for tumor samples. My doubt and question for you is about the minimum reliable coverage we can use for sequencing the germline DNA. In theory, lowering the coverage for the germline would m ...
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