User: Maverick77

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Maverick770
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Posts by Maverick77

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Comment: C: GATK genomicsDBimport intervals for WGS
... If you do have to do them all separately, can they all be gathered up and easily studied together when joint-called using GenotypeGVCFs? ...
written 4 weeks ago by Maverick770
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Comment: C: GATK genomicsDBimport intervals for WGS
... Will this also be the case for exome data? Ideally I'd like to run all chr's at once too. A second question, what would the syntax be for the X and Y chr's - Is it chrX, chrY or X, Y? ...
written 4 weeks ago by Maverick770
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Comment: C: How to conduct germline sharing WES analysis of three probands in a large family
... Indeed, it doesn't really matter that they're related. It's basically looking at a trio and seeing what is different in the proband compared to the parents. And then comparing that specific difference to see if it can be found in the other 2 probands ...
written 4 weeks ago by Maverick770
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How to conduct germline sharing WES analysis of three probands in a large family with the same tumour type.
... I have a question regarding sharing. Is there a 'sharing of the same putitative genes across 3 probands' type of tutorial or pipeline you could point me to? I essentially have exome data for a trio and 2 other probands in a large family who have all been affected by a certain rare cancer type. The ...
germline variant analysis exomes written 4 weeks ago by Maverick770

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