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Posts by alexeigurevich
... We tried Mauve in the beginning of QUAST project but in our experiments (we worked with bacterial genomes) it was 5-10 times slower than Nucmer. Maybe it would be better on human size genomes but I'm not sure about it. I think we will try it and other alignment tools and maybe will change our core a ...
... Yes, you are right that evaluating of human assembly is a challenge for QUAST because it uses Nucmer. However, it is feasible and QUAST tries to make it as fast as possible. Nucmer has a limit on a reference genome size equaled to 536 Mbp which is insufficient for human assembly (approx. 3 Gbp). To ...
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