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replies
11
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Forum: Gene ontology and homologs
geneontology bioinformatics gene
24 minutes ago by beshka194 • 0
5
votes
4
replies
373
views
Forum: Ideal PC configurations and operating system for bioinformatics laboratory
PC
3 days ago by Estevão • 0
0
votes
0
replies
178
views
Forum: Improvement on automatic annotation of single-cell RNA-seq data from the literature using LLM
annotation scRNA llm
12 days ago by yxwucq • 0
4
votes
2
replies
324
views
Forum: Bioinformatics: Where do I start
Sequencing
updated 19 days ago by 43k • written 19 days ago by ▴ 10
7
votes
7
replies
1.5k
views
Forum: Bioinformatician who was retaliated against after reporting discriminatory harassment - Please help me navigate getting out of the situation I'm in
Career advice
updated 20 days ago by ★ 2.5k • written 20 days ago by • 0
1
vote
2
replies
366
views
Forum: VCF bulk handling
bcftools SnpEff WGS VEP VCF
18 days ago by Javier • 0
16
votes
10
replies
1.1k
views
6 follow
Forum: F*up Night style events for Bioinformatics ? Comment if you're interested!
mistakes
updated 5 weeks ago by 5.3k • written 5 weeks ago by ★ 2.4k
1
vote
1
reply
232
views
Forum: Can I use this community for software development?
software-development
updated 5 weeks ago by 43k • written 5 weeks ago by • 0
5
votes
2
replies
397
views
Forum: Can questions and answers on biostars be asked only in English? Can't I use Russian for example?
language
updated 5 weeks ago by 54k • written 5 weeks ago by • 0
0
votes
0
replies
182
views
Forum: Field of Study in Computational Biology
Genomics Computational-Biology PhD
updated 6 weeks ago by 43k • written 6 weeks ago by • 0
1
vote
3
replies
490
views
Forum: Development plan for a bioinformatics database developer/coder
developer
7 weeks ago by pixie@bioinfo ★ 1.5k
7
votes
8
replies
724
views
Forum: Bioinformatics career transition
career forum
updated 7 weeks ago by ★ 16k • written 7 weeks ago by ▴ 20
4
votes
2
replies
500
views
Forum: Exploring Amino Acid Patterns in Proteins Through N-gram Analysis
protein CAFA5
8 weeks ago by Anatoly A. ▴ 10
6
votes
6
replies
792
views
Forum: You have 3 days of zero obligations and expansive resources. What are you building?
hypothetical thought-experiment
8 weeks ago by jared.andrews07 ★ 16k
0
votes
0
replies
172
views
Forum: What other data types and pipelines you would like to see from the Genomics Data Commons (GDC)
gdc tcga genomics-data-commons
updated 8 weeks ago by 43k • written 8 weeks ago by ★ 1.2k
0
votes
2
replies
402
views
Forum: What's the state of the art in bacterial whole genome alignment?
whole genome alignment mauve
8 weeks ago by Dave Carlson ★ 1.7k
31
votes
12
replies
1.0k
views
7 follow
Forum: Nextflow and self-made pipelines opinion
nextflow pipeline data-analysis
9 weeks ago by karlaarz ▴ 90
5
votes
4
replies
579
views
Forum: Would reaching out to local labs and startups help with my career transition?
career volunteering
updated 10 weeks ago by 142k • written 10 weeks ago by ▴ 10
1
vote
2
replies
384
views
Forum: Exploring Career Reentry: Challenges and opportunities for Women After Maternity and Childcare Breaks
Maternity Career-Gap career-reentry
updated 10 weeks ago by 82k • written 10 weeks ago by ▴ 20
8
votes
7
replies
829
views
6 follow
Forum: Tower Server configuration for NGS data analysis
NGS
updated 10 weeks ago by ▴ 120 • written 3 months ago by • 0
1
vote
0
replies
291
views
Forum: list of bioinformatics tools in cancer genomics
mutations CNA cancer genomics LOH
updated 11 weeks ago by 161k • written 11 weeks ago by ★ 1.4k
4
votes
2
replies
390
views
Forum: bulk seq vs. sc-seq
scATAC-seq ATAC-seq scRNAseq RNAseq
updated 12 weeks ago by ★ 6.0k • written 12 weeks ago by ▴ 10
8
votes
6
replies
2.8k
views
Forum: Demonstrating Exponential Growth In Pre-School
education
written 10.2 years ago by 10k
0
votes
0
replies
211
views
Forum: tutorial for carrier screening analyses?
carrier-screening
updated 3 months ago by 43k • written 3 months ago by ▴ 20
2
votes
3
replies
446
views
Forum: My Project
Project CLI MD-Simulations Molecular-docking
3 months ago by Ajay A Shettigar • 0
17
votes
11
replies
1.0k
views
Forum: How to overcome the imposter syndrome in bioinformatics?
advice
3 months ago by sil_bioinfo ▴ 40
10
votes
7
replies
2.2k
views
Forum: How to learn bioinformatics?
learning
updated 3 months ago by ★ 1.3k • written 23 months ago by ▴ 20
26
votes
27
replies
2.1k
views
10 follow
Forum: Determining computer time required
computer hpc time
updated 3 months ago by ★ 6.0k • written 3 months ago by ▴ 40
7
votes
6
replies
748
views
Forum: where to work as a bioinformatician (NGS/IA)
employment omics ia ngs
updated 3 months ago by 43k • written 3 months ago by ▴ 20
21
votes
12
replies
3.6k
views
Forum: How to Use Biostars Part-3: Formatting Text and Using GitHub Gists
meta how-to documentation
3 months ago by Ram 43k
2
votes
1
reply
441
views
Forum: Cataloguing available spatial transcriptomics tools, then linking them together into a workflow?
cytassist transcriptomics nanostring xenium visium
3 months ago by LauferVA 4.2k
49
votes
20
replies
2.1k
views
10 follow
Forum: First experiences matter
first-time tolerance
updated 3 months ago by ★ 2.6k • written 4 months ago by ★ 27k
4
votes
3
replies
789
views
Forum: How to get started in bioinformatics
students
updated 3 months ago by 43k • written 4 months ago by ▴ 10
2
votes
2
replies
592
views
Forum: Do batches contain biological variations in omics data (RNAseq or scRNAseq)?
combat single-cell omics batch rnaseq
updated 4 months ago by 43k • written 4 months ago by ▴ 40
0
votes
2
replies
3.2k
views
Forum: I’m considering a career transition from software engineering to bioinformatics. Is it a good fit for me?
career
updated 4 months ago by 142k • written 4 months ago by ▴ 10
5
votes
3
replies
623
views
Forum: Binning the rare biosphere
metagenomics soil assembly techniques binning
updated 4 months ago by ★ 27k • written 4 months ago by ▴ 20
6
votes
2
replies
676
views
Forum: how to start Bioinformatics?
basics
updated 4 months ago by ★ 27k • written 4 months ago by • 0
19
votes
5
replies
1.1k
views
6 follow
Forum: What Are The Most Influential Bioinformatics/Computational Biology Papers Of 2023?
genomics snps survey papers
4 months ago by Raony Guimarães ★ 1.4k
4
votes
6
replies
940
views
6 follow
Forum: Bioinformatics: what do you think of it in the next 20 years?
future
updated 5 months ago by 43k • written 5 months ago by • 0
1
vote
1
reply
498
views
Forum: want to work in open source project/project in bioinformatics
project
updated 5 months ago by 43k • written 5 months ago by • 0
3
votes
5
replies
1.0k
views
Forum: Current Trends in Bioinformatics
structural-bioinformatics
updated 5 months ago by 43k • written 6 months ago by • 0
21
votes
11
replies
2.5k
views
6 follow
Forum: Rust bioinformatics projects ideas
projects scRNA-seq RNA-seq Rust
updated 5 months ago by 22k • written 14 months ago by ▴ 150
176
votes
46
replies
19k
views
26 follow
Forum: Crac: Funny And/Or Weird Names For Bioinformatics Tools
humor
5 months ago by Istvan Albert 100k
3
votes
2
replies
632
views
Forum: RNA-Seq data analysis - question
Python RNA-Seq R
updated 6 months ago by ▴ 10 • written 6 months ago by ▴ 40
0
votes
0
replies
379
views
Forum: How to learn bioinformatics online?
self-education education learning
updated 6 months ago by 43k • written 6 months ago by • 0
6
votes
5
replies
2.3k
views
Forum: Maintaning internal or private installation of Biostar or a similar Q&A site
Biostars
6 months ago by tshtatland ▴ 190
7
votes
9
replies
1.4k
views
6 follow
Forum: Mentor for a beginner bioinformatics student
project mentor
6 months ago by UT_FAN ▴ 40
0
votes
0
replies
469
views
Forum: Steps after doublet detection in single cell data
scRNA doublet
6 months ago by ishwarvh • 0
0
votes
0
replies
363
views
Forum: Automated Checks And QA
retrospective
6 months ago by Sasha ▴ 840
7
votes
13
replies
1.4k
views
Forum: How do you validate and verify your pipeline's software updates?
Validation Verification Quality-Assurance
updated 6 months ago by 43k • written 7 months ago by ▴ 10
1,000 results • Page 1 of 20
Recent Votes
A: Fold change - a final explanation
Answer: sc/snRNASeq using cell ranger parameters
mitochondria in single nuclear RNAseq
Answer: Association study using SNP data
Comment: agilent human all exon sureselct v7 bed file
Answer: install package
Comment: Overlap File for RACON Genome Polisher
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Commentator to andres.firrincieli 3.6k
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Recent Replies
Comment: TaxID mapping file by Lada ▴ 30
if I understood correctly, I might need fle `prot.accession2taxid.gz` file? According to the [documentation][1] in column 2 is Accession.ve…
Answer: install package by Pine ▴ 10
To follow on Mathew's reply, one way might be to try and see if you can download and install the package tarball locally: 1. Get the packag…
Comment: agilent human all exon sureselct v7 bed file by MiladAD ▴ 10
God bless you man.
Answer: install package by Mathew ▴ 50
Hi, This is what happens when I run some code to diagnose the issue. First, I wanted to see what version of R was required for the package…
Comment: TaxID mapping file by Lada ▴ 30
thank you, I'll look at these files/documents. .
Answer: LD-prune variants while maintaining a list of SNPs by Jautis ▴ 540
I was given a solution by a colleague -- it seems a little hacky, but worked really well! > one way to get this to work is to use --clu…
Answer: Association study using SNP data by drajangirija • 0
Hi Matthew, Thank you very much for your inputs. I am working with Neogen genotyping data, which includes GC values less than 0.15.
Comment: Downloading full alignments from Pfam by bef1 • 0
I tried contacting Pfam, they replied that indeed there is an issue on their side with the full alignments, which should be repaired in the…
Comment: Seeking Bioinformatics/Drug Design Opportunities - PhD in Pharmacology with Expe by Mensur Dlakic ★ 27k
Don't know about others, but I would never contact someone about potential employment based only on their interests and with zero knowledge…
Comment: The GDC Legacy Archive is retiring soon. by Zhenyu Zhang ★ 1.2k
If you are talking about methylation idat files, they were all migrated from legacy to the data portal. If you are talking about other pl…
Comment: How to access TCGA samples that were treated with a specific drug? by Zhenyu Zhang ★ 1.2k
These TCGA samples were taken 10 ~ 20 years ago, and there is no way they have been treated by the modern immunotherapy. Are you sure tha…
Comment: Design matrix Differential expression analysis by Gordon Smyth ★ 7.1k
> When is it recommended to use the design <- cbind(Intercept=1,Group=c(-1,-1,-1,1,1,1)) It is not recommended. No such code appears anywh…
Comment: GRCh38.gmap file by lorena9132 ▴ 10
Hi Mathew, The .txt files provided in the link differ from the .gmap files, but after several attempts, I succeeded in generating the .gma…
Answer: GRCh38.gmap file by Mathew ▴ 50
Hi, I have spent some time searching for a GRCH38 map file for you. I have found a certain publication that uses a hg38 genetic map file…
Answer: Association study using SNP data by Mathew ▴ 50
Hi, You asked three questions so I will attempt to help the best I can **What should be the optimal GC score cutoff** It sounds li…
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