How to find overlap of clusters in two seurat porject

Question

[J]

I have two seurat objects with two sets of data from the same sample, but different sequencing methods. One is ONT, the other is Illumina. Then I got two clustering groups. How to find the overlap cluster in these two groups. For example, cluster 1 in group 1 match cluster 2 in group 2?

Thanks

Answer 1

[Adam]

I think your best bet would be to use annotation mapping. You can use the features of your clusters in group 1 and apply them to group 2 to re-classify. Then you can see which cells would belong to cluster 1 and cluster 2. Checkout this vignette.