Is there an integrated way to analyse mutation data and protein expression data
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7.8 years ago
ShirleyDai ▴ 50

Hi, I have two types of data, say: 1) genome wide DNA mutation data by next-gen sequencing. 2) several protein expression data from the same sample by immunohistochemical analysis Is there a best way (suitable r package) to analyse these data?

Thanks

next-gen mutation immunohistochemistry • 1.3k views
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Answers to these will help determine how best to approach the data analysis.

  • What question do you want to answer with your data?
  • Is the information from IHC quantitative, or just qualitative (present/absent)?
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My hypothesis is the differences of mutation load exist between high expression marker and low expression marker. My IHC data was classified qualitatively as high or low.

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