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                    6.9 years ago
        Molly_K
        
    
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    60
    I have performed eQTL with matrix eQTL tool before with hard call genotype. I wonder if anyone has tried with dosage genotype. The data format is
SNP  A1  A2   F1 I1       F2 I2        F3 I3
     rs0001   A   C   0.98 0.02   1.00 0.00    0.00 0.01 
     rs0002   G   A   0.00 1.00   0.00 0.00    0.99 0.01
Can I just use this file as input? F1 I1 are usually using the same ID, so the file looks like
 SNP  A1  A2   ID01 ID01       ID02 ID02       ID03 ID03
     rs0001   A   C   0.98 0.02   1.00 0.00    0.00 0.01 
     rs0002   G   A   0.00 1.00   0.00 0.00    0.99 0.01
Can matrix eQTL identify the matching individual? or I need a different genoytpe format, if so, what kind? Thank you!