Could someone offer an explanation to how DiffBind calculates its p- values.
Being that p-values consider variance, how does DiffBind, dba.analyze () measure variance between the peaks in replicates.
Ive reached this question because the Volcano Plot of "log10FDR v log2diff binding" did not have much scatter. It seems as if FDR and log2diff between my conditions have a linear relationship.