What do they mean by "multidomain" and "multimetric"?
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23 months ago
user366312 ▴ 20

AlphaFold2: Why It Works and Its Implications for Understanding the Relationships of Protein Sequence, Structure, and Function

In the above article, what did they mean by the terms "multidomain" and "multimetric" in the case of proteins?

protein protein-structure protein-structure-prediction • 565 views
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23 months ago
Mensur Dlakic ★ 27k

Multidomain - multiple protein domains in the same protein. Most eukaryotic proteins are like that.

Multimeric (not multimetric) - multiple proteins that interact together and form some kind of a complex. Can be either homomultimers (identical subunits interacting) or heteromultimers (different subunits interacting).

You have been at this for quite some time, and I am surprised that you never encountered these terms. Or are you just extra cautious as a relative beginner?

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You have been at this for quite some time, and I am surprised that you never encountered these terms. --- my background is in electrical engineering. I am learning this by self-study.

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