gene pLI score

Question

[cocchi.e89]

I am trying to retrieve pLI score for some human genes but I am not able to find a DB of this score. Does anybody knows how to retrieve such data for a specific gene?

Answer 1

[LChart]

The pLI score (now deprecated by the ExAC o/e score). You can pull these tracks (pLI and oe) from UCSC:

https://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg19&g=gnomadPLI

and downloaded here:

http://hgdownload.soe.ucsc.edu/gbdb/hg19/gnomAD/pLI/