Chance that DNA with 3N nucleotide encodes 2 protein with size of N amino-acids in different frames?
0
0
Entering edit mode
12 months ago
Lasha ▴ 10

For each DNA there is 6 possible frame, thus 6 different protein can be coded (3 for parallel transcribing genes + 3 for anti-parallel transcribing genes). I'm trying to calculate the rough estimation for 2 independent protein with the same length, what is the chance there exist at least 1 DNA which codes both? Basically, I have 2 questions: (i) is my estimation correct based on my simplified assumptions or are some assumptions "too rough"? (ii) can I include it in my research? or will this data be useful for you as a research reader (research is about intrinsic regions of dual-coding genes)? enter image description here

probability DNA estimation statistics proteins • 685 views
ADD COMMENT
0
Entering edit mode

hard to completely understand... very obviously you aren't going to encode a protein without a start codon... so you need to factor that into the math

ADD REPLY
0
Entering edit mode

I can explain if you are stuck at a certain point. I'm ignoring the start codon, as these regions which I'm going to evaluate are sub-intervals on their coding sequence (CDS), so it's only important that this sequence must hold 2 protein sequence data.

ADD REPLY
0
Entering edit mode

but so you have a 60% chance that with 3-nt you encode the same protein?

ADD REPLY

Login before adding your answer.

Traffic: 2103 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6