What do I download from the GDC Data portal for a methylation analysis? Files or Cases?
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10 months ago

I have to replicate the analysis in this paper- Genome-Wide Identification and Analysis of the Methylation of lncRNAs and Prognostic Implications in the Glioma I would really appreciate some help in the process. As it is a 3 year old paper I am going to the sites mentioned in the paper and collecting the current data. They had taken data from TCGA and TANRIC. They downloaded the TCGA Data through GDC Data portal. At the GDC Data portal after applying filters mentioned in the paper there are DNA Methylation files and DNA Methylation cases which should I download? I am trying to download files but can not see the download icon. And there are many files and cases is it possible to analyse on our own laptop?

NGS • 559 views
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"Particularly, we selected “DNA methylation” in the Data Category, “Illumina human methylation 450” in the Platform, “brain” in the Primary Site, and “gliomas” in the Disease Type to screen out the methylation information of patients. Then, we selected “clinical” in the Data Category, “brain” in the Primary Site, and “gliomas” in the Disease Type to screen out the clinical information of patients."

So they selected two types of files : 1)DNA methylation data and 2)Clinical information on patients

To download files you can add the selection of files you need to your cart, then go to your cart and click on the download button.

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Thankyou for your help. I used the filters given in the paper and was able to screen out. I have also found the download button. As you have looked at the paper which one of the projects from the GDC Portal have been used in this paper? When you search in GDC There are 3 projects that come up. The first 2 are TCGA GBM and TCGA LGGI am sure it is one of these that is used in this paper or both could you please confirm if possible.

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It is not indicated that they applied selection on project

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