Is it possible to detect fusion genes by either stranded or unstranded RNA-seq?
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6 months ago
Apprentice ▴ 160

I am interested in detecting fusion genes in RNA-seq data. I'm going to use STAR-Fusion. There are two types of RNA-seq, stranded RNA-seq and unstranded RNA-seq. Is it possible to detect fusions in either of these two types? I would appreciate it if you could enlighten me.

RNA-seq STAR-Fusion • 403 views
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6 months ago
dsull ★ 5.5k

Yes, you can detect fusions in both.

Stranded has the advantage that you can find whether an RNA-seq read originated from the plus or minus strand of the DNA template. This has nothing to do with fusion.

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Thank you for your quick guidance!

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