Using the Same Background for ATAC-seq Peak Calling Across Two Samples
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2.1 years ago
David • 0

Hello,

I'm currently working with two samples of ATAC-seq data (each one has 3 replicates), and I'm interested in calling peaks ensuring that both samples utilize the same background. This is to achieve consistent detection of accessible chromatin regions across the two datasets.

Has anyone tried this approach or can provide guidance on best practices? Are there any tools or methods specifically recommended for this?

Any insights or experiences shared would be greatly appreciated. Thank you in advance!

Best,

ATAC-seq peak-calling chromatin-accessibility • 490 views
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