Need assistance in proper binding of cysteines
0
0
Entering edit mode
6 months ago
Kirill ▴ 10

Hello!

I am newbie in protein building and i need to create disulfide bond between newly builded cysteine and another one to form active site for my ligand. Further i need to dock small molecule in this site.

Is there any tools to create such bond? Maybe MODELLER and it's model-disulfide.py script? Is CHIMERA and PyMOL editing not only visualization but coords in PDB file?

Thanks in advance!

Protein modelling • 351 views
ADD COMMENT
0
Entering edit mode

I think this should be possible with Chimera (although admittedly I never added this specific bond), a quick Google search showed me this tutorial. Probably section II will be of use for you?

ADD REPLY

Login before adding your answer.

Traffic: 1640 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6