I am currently in need of guidance in selecting appropriate computational tools to map potential epitope regions using mimotope-based methods. After a review of the literature and existing resources, I have found that tools such as MIMOX (an online service) and 3DEX, among others, are not currently available. If any of you have experience or knowledge of other suitable computational tools that use this combinatorial approach to map epitopes, which require both phage display peptide sequences and the three-dimensional structure of the antigen, I would greatly appreciate your ideas and recommendations. On the other hand, if anyone has any suggestions for a different structural approach that maintains the comparison of the mimotopes with the three-dimensional antigen-containing structure, I would also appreciate it.
