Interpreting Pathway 7049: Fatty Acid Salvage in PICRUSt2 Results from Nephele

Question

[benkosta]

Hi everyone,

I ran PICRUSt through Nephele to analyze functional pathways in my microbial community data. In the results, I noticed that Pathway 7049: Fatty Acid Salvage appears among the pathways with the highest fold change (as shown in the attached screenshot).

Does this indicate that Fatty Acid Salvage is more activated in one group compared to the other?

Is there a difference between fold change and log2 fold change, or are these terms used interchangeably in the context of pathway analysis?

Thank you for your help!