EggNOG mapper annotation results
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2.6 years ago
F.Bedjou ▴ 20

I am new with Bioinformatics, I used eggnog to annotate a group of protein sequences

The results obtained with eggnog are not very well explained, how do you interpret these results? Query | seed_ortholog | evalue | score | eggNOG_OGs | max_annot_lvl | COG_category | Description | Preferred_name | GOs | EC | KEGG_ko | KEGG_Pathway | KEGG_Module | KEGG_Reaction | KEGG_rclass | BRITE | KEGG_TC | CAZy | BiGG_Reaction | PFAMs

for exemple with those GOs results how can I get a Nice graph like those seen in publication?

each case correspend to one querry, I have on annotation results a set of GO ID: how it can be possible ? how to know to wich term it correspend? GOs GO:0000122,GO:0000128,GO:0000228,GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0001012,GO:0001067,GO:0001085,GO:0001103,GO:0001558,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006355,GO:0006357,GO:0008134,GO:0008150,GO:0009268,GO:0009405,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010570,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016458,GO:0019219,GO:0019222,GO:0030308,GO:0030447,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0035690,GO:0036176,GO:0036177,GO:0036178,GO:0036180,GO:0036244,GO:0040007,GO:0040008,GO:0042221,GO:0042493,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0043900,GO:0043901,GO:0044182,GO:0044212,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045892,GO:0045893,GO:0045926,GO:0045934,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0051716,GO:0060255,GO:0060256,GO:0060257,GO:0060258,GO:0065007,GO:0070013,GO:0070491,GO:0070784,GO:0070785,GO:0070887,GO:0071214,GO:0071467,GO:0080090,GO:0097159,GO:0098630,GO:0098743,GO:0104004,GO:0140110,GO:1900428,GO:1900429,GO:1900460,GO:1900462,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000217,GO:2000218,GO:2000220,GO:2000221,GO:2001141 ....etc

thank you in advance

GO COG EC Eggnog • 2.0k views
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I have the same question .... Did you figure it out?

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This is normal. Each protein can participate in multiple biological processes, have multiple molecular functions, and be part of different cellular components. That’s why the annotation gives you a comma-separated list of GO IDs.

For example: GO:0006355--> regulation of transcription, DNA-templated

GO:0005634--> nucleus

GO:0003677 --> DNA binding

Together, this says: "This protein is a DNA-binding transcription regulator in the nucleus."

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