Germline and somatic mutations TCGA (GDC Data Portal)
0
0
Entering edit mode
8 hours ago

Hi everyone

I want to train a machine learning model to find somatic mutations in RNA data. For this I need clearly labeled somatic and germline mutations from WXS. I have access to the data on TCGA. Regarding somatic mutations: I think these are the PASS variants in the mutect2 vcf of WXS tumor-normal paired data, if I understand correctly. But I also need confidently called germline mutations, are these the PASS variants from the normal only sample?

Some help figuring this out would be really appreciated

Thanks in advance!

Kind regards Charlotte

germline somatic TCGA mutation • 49 views
ADD COMMENT

Login before adding your answer.

Traffic: 6165 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6