User: Vincent Laufer

gravatar for Vincent Laufer
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920
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51 minutes ago
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3 years, 10 months ago
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Posts by Vincent Laufer

<prev • 163 results • page 1 of 17 • next >
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Function returning % trait explained given effect size and MAF for complex trait
... Hello all, Is there a function written in R or another language of the form: Variance_Explained<-get_var_exp(effect_size, minor_allele_frequency, [other args]) Specifically, on page 25 of the supplemental methods of Stahl et al. 2012 (see https://www.nature.com/articles/ng.2232 ), an equation ...
R genetic variance explained risk score written 1 day ago by Vincent Laufer920
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Comment: C: Co-occuring mutations analysis
... this question could mean almost anything. any software program including a function or two dealing with linkage disequilbrium technically meets this definition. do you have a more specific question? perhaps relating to a given field such as cancer biology? ...
written 3 months ago by Vincent Laufer920
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Comment: C: High-quality visualization of GSEA data illustrating relationships between multi
... yes i can do this, however it does not address the questions as posted above. ...
written 4 months ago by Vincent Laufer920
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High-quality visualization of GSEA data illustrating relationships between multiple pathways.
... I am finishing up a collaboration for a group for whom I have been analyzing some RNA sequencing data. I have already generated the "standard" figures for GSEA analysis, (e.g. barcode plots, leading edge heatmaps, a joyplot, and a few other things that visualize **individual pathways.**). What I ...
figure gsea written 4 months ago by Vincent Laufer920
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Comment: C: Deseq2 question of a single factor with 3 levels
... It may be time to consider this. Although I agree that *most* people who crosspost without explicitly saying it is a crosspost necessitate unnecessary work for the community, it is also the case the crossposting can help internet communities provided that those queries are linked. Therefore althou ...
written 5 months ago by Vincent Laufer920
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Comment: C: Deseq2 question of a single factor with 3 levels
... Does this website have a formal policy on etiquette for crossposting? ...
written 5 months ago by Vincent Laufer920
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Comment: C: How to keep a log of columns removed from edited MSA?
... Please provide a sample of one of the input MSA files and the desired output file. ...
written 6 months ago by Vincent Laufer920
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Comment: C: Conditioning association summary statistics using a correlation matrix.
... @Jean-Karim - Thank you for your post. I will reflect on this. I will conduct a search on my own. However, if you have any manuscripts or even textbooks in mind, I will be sure to take a look at those too. ...
written 7 months ago by Vincent Laufer920
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Comment: C: Conditioning association summary statistics using a correlation matrix.
... Note, I posted a more technical (mathematical) description of the goal here: https://stats.stackexchange.com/questions/317310/using-correlation-structure-to-predict-association-strength-after-conditioning-o ...
written 7 months ago by Vincent Laufer920
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Conditioning association summary statistics using a correlation matrix.
... I am conducting a meta-analysis of genetic data, and I am also fine-mapping a few loci to try to determine which variants are the pathogenic or "causal" variants. In some of these loci, there have been studies done demonstrating at least one pathogenic variant, but in several of these cases there a ...

Latest awards to Vincent Laufer

Popular Question 8 weeks ago, created a question with more than 1,000 views. For Odds Ratio Confidence Intervals in SNP Test
Guru 8 weeks ago, received more than 100 upvotes.
Popular Question 12 weeks ago, created a question with more than 1,000 views. For Odds Ratio Confidence Intervals in SNP Test
Good Answer 9 months ago, created an answer that was upvoted at least 5 times. For A: hypergeometric distribution for proximal gene enrichment
Scholar 14 months ago, created an answer that has been accepted. For A: Delete Text between two strings sed, awk
Teacher 14 months ago, created an answer with at least 3 up-votes. For A: Hardy-Weinberg assumptions in variant calling
Popular Question 15 months ago, created a question with more than 1,000 views. For Selection of a "suggestive" level of association in a GWAS study
Popular Question 17 months ago, created a question with more than 1,000 views. For List of causal variants for autoimmune diseases
Voter 17 months ago, voted more than 100 times.
Popular Question 18 months ago, created a question with more than 1,000 views. For Best implementation of negative binomial association test for GWAS data?
Popular Question 18 months ago, created a question with more than 1,000 views. For Rationale for including a certain number of PCs in a GWAS study?
Teacher 18 months ago, created an answer with at least 3 up-votes. For A: Hardy-Weinberg assumptions in variant calling
Popular Question 21 months ago, created a question with more than 1,000 views. For Options for generation of publication quality gene diagrams with annotation
Popular Question 22 months ago, created a question with more than 1,000 views. For Options for generation of publication quality gene diagrams with annotation
Appreciated 23 months ago, created a post with more than 5 votes. For A: hypergeometric distribution for proximal gene enrichment

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