User: Denise - Open Targets

Reputation:
4,640
Status:
Trusted
Location:
UK, Hinxton, EMBL-EBI
Website:
http://www.ebi.ac.uk/a...
Twitter:
@deniseOme
Scholar ID:
Google Scholar Page
Last seen:
1 day, 7 hours ago
Joined:
3 years, 11 months ago
Email:
r*******@yahoo.com

I'm currently leading the Outreach activities for Open Targets at EMBL-EBI with my love of genetic variants, genomes, science communication, and user support. Learning about early drug discovery and disease biology. Past: Ensembl, Wellcome Sanger Institute, Australian National University and Federal University of Minas Gerais.

Posts by Denise - Open Targets

<prev • 488 results • page 1 of 49 • next >
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Comment: C: Best Bioinformatics Tools & Databases Targeting Genetics Disorders
... Yes, we do have plans to include disease prevalence in the Disease profile page such as the profile page for [Duchenne muscular dystrophy][1]. This would come from WHO and Orphanet. However we cannot give you a timeline for this... As per HI genes we may be able to add this annotation to our Target ...
written 11 days ago by Denise - Open Targets4.6k
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Answer: A: Best Bioinformatics Tools & Databases Targeting Genetics Disorders
... To elaborate on @EricLim suggestion, the Open Targets Platform uses genetics, omics and chemical information to associate genes (our proxies to drug targets) with diseases (both Mendelian, rare diseases and more common, complex ones). [Open Targets is also available in programmatic access][2] with o ...
written 11 days ago by Denise - Open Targets4.6k
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Comment: C: We are looking for a software engineer and a senior scientific programmer to wor
... Done. More precisely Hinxton, outside Cambridge UK. ...
written 5 weeks ago by Denise - Open Targets4.6k
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Comment: C: GWAS summary file including risk allele, protective allele and disease
... No, the authors not always provide this information to the journal or make it available through supplementary materials. I'd have thought that some of the info you are after is available Ensembl, known as "associated allele" in the "[Phenotype data][1]" table for a given rsID. [1]: http://www.ens ...
written 5 weeks ago by Denise - Open Targets4.6k
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Comment: C: Where Can I Find GERMLINE Mutation Databases Specialized In CERVICAL Cancer?
... Try the [Open Targets Platform][1]. It's not a germline mutation database, but it does integrate and score germline variants (including mutations) as well as other types of data to associate diseases e.g. cervical carcinoma with targets (aka genes/proteins). The current version shows germline varia ...
written 5 weeks ago by Denise - Open Targets4.6k
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Comment: C: How can I figure out the NCBI annotation version of a GFF file?
... This could give you some clues: * chicken ([release 102][1] from 2016?) * cattle ([release 104][2] from 2017? if it's *B. taurus*) * pig ([release 105][3] from 2017?). [1]: ftp://ftp.ncbi.nih.gov/genomes/Gallus_gallus/ARCHIVE/ANNOTATION_RELEASE.102/ [2]: ftp://ftp.ncbi.nih.gov/genomes/Bos_ta ...
written 5 weeks ago by Denise - Open Targets4.6k
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Answer: A: the track part of UCSC table browser
... Tracks are different annotations that can be added to your view in the UCSC genome browser; so it's really up to you which one to choose. They are aligned to the genome and can be either computed by UCSC or provided by others. Do you want the ab initio prediction only? Then, choose AUGUSTUS. Are yo ...
written 5 weeks ago by Denise - Open Targets4.6k
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Job: We are looking for a software engineer and a senior scientific programmer to work in Open Targets, Hinxton UK
... We have two exciting job openings to work with [Open Targets][1] and our collaborators at the EMBL-EBI. A) As a [software engineer][2] in the Open Targets Core team, you will be involved in analysing and integrating large-scale biological data, and contributing to the development of the [Open Targe ...
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Comment: C: What can be considered as novelty in GWAS?
... Have you thought in discussing this with "them"? Remind your job role to them? I understand "their" ("our"?) need to publish. It's our PhD thesis. It's for our grant. It's for our tenure. It's for our next job. The "publish or perish" is still on. We can rarely publish something that is not novel ...
written 6 weeks ago by Denise - Open Targets4.6k
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Comment: C: free DATABASE FOR SNP's for diabetes mellitus 2
... In addition to BioMart and depending on which information exactly you are after for all these SNPs for T2D, you can try the [Open Targets Platform][1]. We use SNPs from GWAS, and many other [data sources][2], to link genes to diseases e.g. [type II diabetes mellitus][3]. These SNPs are known by us ...
written 8 weeks ago by Denise - Open Targets4.6k

Latest awards to Denise - Open Targets

Teacher 3 days ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Popular Question 3 months ago, created a question with more than 1,000 views. For Open Targets and programmatic access
Scholar 4 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Teacher 5 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Teacher 6 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Popular Question 7 months ago, created a question with more than 1,000 views. For Open Targets and programmatic access
Popular Question 7 months ago, created a question with more than 1,000 views. For Open Targets and programmatic access
Teacher 9 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Commentator 12 months ago, created a comment with at least 3 up-votes. For C: Find an gene as an example of how the human is related to other primates with bl
Teacher 13 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Scholar 15 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Good Answer 15 months ago, created an answer that was upvoted at least 5 times. For A: why drop out the protein coding genes ?
Scholar 15 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Teacher 15 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Popular Question 16 months ago, created a question with more than 1,000 views. For Open Targets, validating targets for drug development in the treatment of diseases.
Teacher 19 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Teacher 19 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Scholar 19 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Teacher 19 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Scholar 19 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Scholar 20 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?

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