User: Denise - Open Targets

Reputation:
4,180
Status:
Trusted
Location:
UK, Hinxton, EMBL-EBI
Website:
http://www.ebi.ac.uk/a...
Twitter:
@deniseOme
Scholar ID:
Google Scholar Page
Last seen:
2 days ago
Joined:
3 years, 4 months ago
Email:
r*******@yahoo.com

I'm currently leading the Outreach activities for Open Targets at EMBL-EBI with my love of genetic variants, genomes, user support, training, and communication in genomics and bioinformatics. Learning about early drug discovery and disease biology. Previously worked in Ensembl and Ensembl Genomes, GENCODE, EUCOMM and Pig Genome projects, with post-doctorate in human population genetics (at the Wellcome Trust Sanger Institute) and sex chromosome evolution (at the Australian National University).

Posts by Denise - Open Targets

<prev • 445 results • page 1 of 45 • next >
0
votes
1
answer
79
views
1
answers
Comment: C: SNP Positioning on a Gene
... What do you mean by efficient way? What is the format of your list of SNPs? Is it a BED file? ...
written 2 days ago by Denise - Open Targets4.2k
0
votes
1
answer
78
views
1
answers
Answer: A: Biomart error: Does anyone know how to solve this error?
... I think the choice of filters (i.e. external_gene_name) is wrong. The LOC is a NCBI gene name. Leave the LOC out and use the numbers only to get NCBI gene ID. LOC511158 is the gene name and 511158 is the NCBI gene ID you should select/input in BioMart. Note that out of the NCBI IDs above I could on ...
written 2 days ago by Denise - Open Targets4.2k
0
votes
1
answer
92
views
1
answers
Answer: C: Mutation position in COSMIC
... Perhaps there are two things going on here: Issue 1) allele A is the ancestral allele (perhaps we would expect it to be the derived allele); Issue 2) COSMIC shows the right genomic coordinate in their [overview][1] page i.e. 1:2558463, but not in the [browser][2] page i.e. 1:2558462-2558463. If I ...
written 2 days ago by Denise - Open Targets4.2k
0
votes
2
answers
726
views
2
answers
Answer: A: What information about VARIANTS are found in biomedical literature rather than d
... You could also get the allele frequencies for genetic variants. Alleles that are rather common are unlikely to have a role in disease, unless it confers some sort of selection (classic example is the variant in HBB in people leaving in regions endemic for malaria). Another piece of information that ...
written 22 days ago by Denise - Open Targets4.2k
1
vote
1
answer
358
views
1
answers
Comment: C: Doctor looking fertility for a collaborator for text mining on pubmed
... If you use the latest Open Targets tool, [LINK][1], and search for endometriosis, these are the [results][2] you get. Scroll down to see the connections with genes, drugs, etc...Check [Get to know LINK and explore 500+ million relations from PubMed abstracts][3] post for more details. Besides `LIN ...
written 22 days ago by Denise - Open Targets4.2k
0
votes
2
answers
303
views
2
answers
Comment: C: Open Source Bioinformatics projects for beginners
... If you have a proposal in mind, you can send it our away. [Open Targets][1] is a public-private partnership that uses human genomics data for systematic drug target identification. If you know Python and can code with confidence, you may want to apply for our python [software developer][2] post. ...
written 22 days ago by Denise - Open Targets4.2k
5
votes
0
answers
172
views
0
answers
Tool: Get to know LINK and explore 500+ million relations from PubMed abstracts
... We have released [LINK][1] (LIterature coNcept Knowledgebase), the latest resource in our Open Targets toolkit. `LINK` is a free resource that allows you to explore more than 500 million relations between genes, diseases, drugs and other key concepts. We have used [natural-language processing][2] ...
open targets drug gene nlp disease tool written 22 days ago by Denise - Open Targets4.2k
1
vote
0
answers
265
views
0
answers
Job: Looking for developers to join Open Targets at EMBL-EBI (fixed term)
... **Hurry up: only 3 days left for your application** We have two exciting opportunities to work in [Open Targets][1] in a startup-like environment, using a wide range of modern technologies, to continuously improve the [Open Targets Platform][2], a genome-wide resource for target identification and ...
open targets python web job api drug written 4 weeks ago by Denise - Open Targets4.2k
0
votes
3
answers
304
views
3
answers
Answer: A: Biopython / Python for genomics data analysis online courses
... I'd recommend [DataCamp][1] and [Using Python for Research][2], both are free of charge. [1]: https://www.datacamp.com/courses/intro-to-python-for-data-science [2]: https://www.edx.org/course/using-python-research-harvardx-ph526x-0 ...
written 11 weeks ago by Denise - Open Targets4.2k
0
votes
0
answers
177
views
0
answers
News: Open Targets API upgrades to a new version, v3
... If you have read our tutorial [Open Targets and programmatic access][1], you will be pleased to know that we upgraded our [API to version 3 for faster drug target discovery][2]. These are the highlights of our latest Open Targets API: * new URL * new methods * new infrastructure (Google App Engine ...

Latest awards to Denise - Open Targets

Teacher 9 weeks ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Commentator 5 months ago, created a comment with at least 3 up-votes. For C: Find an gene as an example of how the human is related to other primates with bl
Teacher 6 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Scholar 8 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Good Answer 8 months ago, created an answer that was upvoted at least 5 times. For A: why drop out the protein coding genes ?
Teacher 8 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Scholar 8 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Popular Question 8 months ago, created a question with more than 1,000 views. For Open Targets, validating targets for drug development in the treatment of diseases.
Teacher 11 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Teacher 12 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Scholar 12 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Teacher 12 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Scholar 12 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Scholar 13 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Teacher 13 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Scholar 14 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Teacher 15 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Good Answer 15 months ago, created an answer that was upvoted at least 5 times. For A: why drop out the protein coding genes ?
Teacher 16 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?
Scholar 16 months ago, created an answer that has been accepted. For A: What is FPG in Genetics?
Teacher 16 months ago, created an answer with at least 3 up-votes. For A: What is FPG in Genetics?

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 660 users visited in the last hour