User: eric.letouze

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Posts by eric.letouze

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How do I calculate the confidence interval of a mutation rate?
... Hi, I am estimating the mutation rates (mutations/Mb) in a series liver tumors. How can I estimate the confidence interval of each mutation rate? I tried using the binomial test (binom.test function in R) but it is quite computation intensive... Any better idea? Thanks you very much in advance, ...
genome R sequence written 4.7 years ago by eric.letouze0 • updated 4.7 years ago by Jean-Karim Heriche23k
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Genotype quality scores in 1000 Genomes vcf files
... Hi, I have downloaded the release 3 of 1000 Genomes data on their ftp server. I would like to apply quality thresholds to keep only SNPs with a good coverage and calling quality for each sample. However the genotype field only contains the genotype itself, without information on read depth and ge ...
snp written 5.8 years ago by eric.letouze0 • updated 5.8 years ago by ngsgene350

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