User: Shicheng Guo

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Shicheng Guo8.5k
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Posts by Shicheng Guo

<prev • 816 results • page 1 of 82 • next >
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Comment: C: Formula of LOEUF: loss-of-function observed/expected upper bound fraction
... Nope! What about you? ...
written 2 days ago by Shicheng Guo8.5k
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Answer: A: Prediction Of Mutation Impact
... AlphaFold V2 increase protein 3D structure prediction accuracy to next level (~90%). AlphaFold received a very high score which is around 90, even for some worst situation, distance score test come up to 80+. You can try to take genetic variants into the model and check what will happen to the new 3 ...
written 27 days ago by Shicheng Guo8.5k
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Comment: C: How to understand Instance and Array in UKB phenotype data
... [Data-Field 5986][1] has 114 array. How to figure out how these 114 array are generated? 5,758,563 items of data are available, covering 95,140 participants. Defined-instances run from 0 to 1, labelled using Instancing 2. Array indices run from 0 to 113. Units of measurement are seconds Thanks Sa ...
written 27 days ago by Shicheng Guo8.5k
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Answer: A: compare two GWAS results
... Create a mirrored Manhattan plot using GWAS data https://github.com/anastasia-lucas/hudson ![enter image description here][1] [1]: https://camo.githubusercontent.com/911f78e8b1ad866b4cc382ecc2c4540d3911c17ab2eda40793ae0e5a8659efa7/68747470733a2f2f692e696d6775722e636f6d2f394c794b5069352e706e67 ...
written 7 weeks ago by Shicheng Guo8.5k
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Timeline for hg39 human genome?
... Hi All, Do we have timeline for human hg39 genome? I ask these questions because I have lots of hg37 data need to transfer to hg38, but I am wondering if hg39 come out soon, then I think I can wait for hg39 version. Thanks ...
hg39 hg38 human written 7 weeks ago by Shicheng Guo8.5k • updated 7 weeks ago by Pierre Lindenbaum133k
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How to understand Structural Variation in bedpe format?
... Hi All, How to understand the structural variation with bedpe format? For example, the first one is duplication, how to know which region is duplicated ? how many duplicates happened? what does start1 and end1 mean? why they are always having 1b difference? chrom1 start1 end1 chrom2 start ...
sv bedpe written 8 weeks ago by Shicheng Guo8.5k
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Comment: C: about inversions: head-to-head and tail-to-tail
... any update to the question? ...
written 8 weeks ago by Shicheng Guo8.5k
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Comment: C: Individual-level data for Million Veteran Program (MVP)
... downloaded the data from dbGAP and find the data is mess. ...
written 8 weeks ago by Shicheng Guo8.5k
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Human developmental expression patterns database?
... Hi All, I want to check the developmental gene expression pattern for some genes of interest. For example, the changes of gene expression pattern in infant, young, adult and old age stage. Thanks. ...
rna developmental human written 8 weeks ago by Shicheng Guo8.5k
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Comment: C: Most important International Big Data Projects: Genetics and Epigenetics
... Hi genomax, do you know how to access individual-level Million veterans project data? ...
written 9 weeks ago by Shicheng Guo8.5k

Latest awards to Shicheng Guo

Great Question 26 days ago, created a question with more than 5,000 views. For trim_galore and cutadapt to paired-end DNA sequencing
Popular Question 4 weeks ago, created a question with more than 1,000 views. For Biomarker for Cancer TNM Stage
Popular Question 5 weeks ago, created a question with more than 1,000 views. For Biomarker for Cancer TNM Stage
Popular Question 6 weeks ago, created a question with more than 1,000 views. For Biomarker for Cancer TNM Stage
Popular Question 7 weeks ago, created a question with more than 1,000 views. For Biomarker for Cancer TNM Stage
Teacher 8 weeks ago, created an answer with at least 3 up-votes. For A: Area under the ROC Curve for genetic data
Epic Question 9 weeks ago, created a question with more than 10,000 views. For Protocol To Downlad TCGA Data From GDC
Popular Question 12 weeks ago, created a question with more than 1,000 views. For Vector NTI in Window 10
Popular Question 3 months ago, created a question with more than 1,000 views. For Vector NTI in Window 10
Appreciated 3 months ago, created a post with more than 5 votes. For A: What is a typical workflow to correlate methylation and expression data?
Popular Question 3 months ago, created a question with more than 1,000 views. For Vector NTI in Window 10
Popular Question 4 months ago, created a question with more than 1,000 views. For Vector NTI in Window 10
Popular Question 4 months ago, created a question with more than 1,000 views. For Vector NTI in Window 10
Popular Question 4 months ago, created a question with more than 1,000 views. For Vector NTI in Window 10
Popular Question 4 months ago, created a question with more than 1,000 views. For LD plot for both microsatellites and SNP data (Haploview)
Popular Question 4 months ago, created a question with more than 1,000 views. For Vector NTI in Window 10
Appreciated 4 months ago, created a post with more than 5 votes. For A: What is a typical workflow to correlate methylation and expression data?
Commentator 4 months ago, created a comment with at least 3 up-votes. For C: Hapmap 3 in hg19/GRCh37 plink format PED and MAP
Popular Question 5 months ago, created a question with more than 1,000 views. For Bismark: Minimum MAPQ threshold (MMT) and Minimum Phred threshold (MPT)
Popular Question 5 months ago, created a question with more than 1,000 views. For Bismark: Minimum MAPQ threshold (MMT) and Minimum Phred threshold (MPT)
Popular Question 6 months ago, created a question with more than 1,000 views. For Bismark: Minimum MAPQ threshold (MMT) and Minimum Phred threshold (MPT)
Popular Question 6 months ago, created a question with more than 1,000 views. For Bismark: Minimum MAPQ threshold (MMT) and Minimum Phred threshold (MPT)
Popular Question 6 months ago, created a question with more than 1,000 views. For Bismark: Minimum MAPQ threshold (MMT) and Minimum Phred threshold (MPT)
Popular Question 6 months ago, created a question with more than 1,000 views. For Bismark: Minimum MAPQ threshold (MMT) and Minimum Phred threshold (MPT)
Popular Question 6 months ago, created a question with more than 1,000 views. For Bismark: Minimum MAPQ threshold (MMT) and Minimum Phred threshold (MPT)

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