User: Bruno Vieira
Posts by Bruno Vieira
How to down-sample a BAM file read depth to reduce heterogeneity in coverage while keeping heterozygosity
... Hi, I want to take I high coverage alignment, like 90x, that has a lot of variation in coverage, and down-sample it to 20x to reduce the variation (i.e., like setting a maximum coverage threshold and cutting all the "peaks" above that coverage in the alignment). Ideally, the removal of reads or ba ...
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