User: Holmes

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Holmes0
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Posts by Holmes

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Comment: C: Geometric Mean of Two Genes in Expression Matrix
... Thank you Akhil, this makes sense. The the paper they uses Transcripts per Million (TPM) count from RNA-seq in calculating the score. The data I'm looking at is a normalized Affy microarray experiment, but I can get the relative signal intensity as well. I am skeptical, however, of using this mea ...
written 18 months ago by Holmes0
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Geometric Mean of Two Genes in Expression Matrix
... Hello, This is probably a very simple question. I am currently working on an expression matrix to replicate a "cytolytic score" in R.[1] The cytolytic score is defined as "geometric mean of GZMA and PRF1". My goal is to then investigate the Pearson's correlation of this score with other genes of ...
R rna microarray rna-seq written 18 months ago by Holmes0 • updated 18 months ago by Ahill1.5k
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Maestro (Schrodinger Software), Protein Data Bank,
... Hi all, I am new to Maestro and have not done structural biology in quite a bit. I am examining protein structures and trying to find ways to determine properties of proteins I look at from PBD (protein data bank).  Please let me know if this topic is not covered in this forum and if there is a bet ...
structural bioinformatics pdb maestro written 3.3 years ago by Holmes0 • updated 3.1 years ago by Biostar ♦♦ 20

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