User: Learner

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Learner 160
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Posts by Learner

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Comment: C: A simple regression in R
... @Kevin Blighe no offend, I am naive for sure and I am learning without any problem. I simply pointed out the issue I see with the built model. No offend whatsoever. I just wanted to inform you about my findings ...
written 10 weeks ago by Learner 160
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Comment: C: A simple regression in R
... @Kevin Blighe you wrote me this `to see if there are cell-line specific effects in relation to drug sensitivity` actually I have been reading a lot about this. no one uses lm for such a analysis. the worse one can do is liner because basically it is not linear but nonlinear and sigmoidal ! however, ...
written 10 weeks ago by Learner 160
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Comment: C: how to calculate the AUC for a drug response in R
... @Kevin Blighe do you know the cell to cell interaction ...
written 10 weeks ago by Learner 160
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Comment: C: how to calculate the AUC for a drug response in R
... @Kevin Blighe could you please use the following data in your example? I am just wondering how you could do that df<-structure(list(Drug_name = structure(c(1L, 1L, 1L, 1L, 1L), .Label = "DrugT", class = "factor"), Cell_line = structure(c(2L, 3L, 1L, 4L, 5L), .Label = c("Celline ...
written 10 weeks ago by Learner 160 • updated 10 weeks ago by Kevin Blighe44k
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Comment: C: how to calculate the AUC for a drug response in R
... @Kevin Blighe, So, let me give more information and see your comments, I will absolutely like and accept your answer even if it does not lead me to a correct answer. So, lets assume that I have a cell line which I treat with a compound in several concentration and I obtain the sensitivity values. If ...
written 11 weeks ago by Learner 160
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Comment: C: how to calculate the AUC for a drug response in R
... @Kevin Blighe Thanks Kevin, I thought that the concentration-response curves is based on the percent-viability scores which is often fit using smooth cubic splines for multivariate data . what I am mainly looking for is to calculate the AUC which should be only a value, right? ...
written 11 weeks ago by Learner 160
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A simple regression in R
... I am looking for a way to calculate AUC for a drug response . The data looks like the following df<- structure(list(Compound = structure(c(1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L), .Label = "A", class = "factor"), conc = c(0.00372, 0.01368, 0.05004, 0.1836, 0.6732, 2.472, 9 ...
R written 11 weeks ago by Learner 160
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Comment: C: evolution of gene
... @pltbiotech_tkarthi thanks a lot for sharing, I am going to read that manuscript ...
written 12 weeks ago by Learner 160
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Comment: C: evolution of gene
... @ jrj.healey THANKS for your constructive message ...
written 12 weeks ago by Learner 160
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Comment: C: evolution of gene
... @RamRS do you know how one could look at the mutation occurrences? Wow that is fascinating ...
written 12 weeks ago by Learner 160

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