Moderator: Malachi Griffith

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Location:
Washington University School of Medicine, St. Louis, USA
Website:
http://www.malachigrif...
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Last seen:
6 days, 8 hours ago
Joined:
7 years, 12 months ago
Email:
m*******@genome.wustl.edu

I am an Assistant Director of the Genome Institute, and Assistant Professor of Genetics at Washington University School of Medicine. I am conducting research in medical genomics and bioinformatics specializing in the application of molecular biology, informatics, and statistics to the study of cancer.

Posts by Malachi Griffith

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Comment: C: Resource for cancer cell line tumorigenicity in mice?
... This resources might be helpful: "PDX FINDER IS YOUR OPEN GLOBAL CANCER RESEARCH PORTAL TO PATIENT DERIVED XENOGRAFT MODELS" ...
written 6 days ago by Malachi Griffith17k
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Tutorial: Resources / databases for clinical interpretation of cancer variants
... BioStars already has some nice posts on data portals for [exploring mutation observations][1] (e.g. GDC, ICGC), [databases of tumor suppressors and oncogenes][2], and [drug-gene interactions][3]. However, these don't quite cover another category of very useful resources for interpreting variants in ...
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Job: Cancer Genomics and Bioinformatics positions at WashU (Griffith Lab)
... We are looking to fill some bioinformatics staff positions. Join a fantastic team (~20 bioinformaticians) working on exciting areas of cancer, genomics, immunotherapy, precision medicine. Our lab is located within the McDonnell Genome Institute at Washington University School of Medicine. We hav ...
immunogenomics bioinformatics job cancer written 10 months ago by Malachi Griffith17k • updated 10 months ago by Chris Miller21k
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News: Workshop for genomic data visualization and interpretation
... We will be delivering a workshop on **advanced R and bioinformatics applications for visualization and interpretation of genomic data**. While the course has advanced modules, we try to start from basic principles and build from there. Many of the genomic data interpretation and visualization prin ...
R news ggplot2 rna-seq genomics written 10 months ago by Malachi Griffith17k
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Comment: C: Comprehensive & integrated drug/target database?
... This post discusses these databases extensively: https://www.biostars.org/p/17392/#17396 ...
written 19 months ago by Malachi Griffith17k
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Comment: C: Exploring cancer mutation data portals
... Other options that are in the vein of DoCM: [Cancer Hotspots][1] Other options that are in the vein of CIViC: Jackson Lab's [JAX CKB][2] MSKCC's [ONCOKB][3] Cornell's [PMKB][4] IRB's [CGI][5] If you would like learn more about efforts to harmonize the efforts of the cancer variant interpretation r ...
written 21 months ago by Malachi Griffith17k
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Comment: C: Exploring cancer mutation data portals
... The reason these portals exist is that in part it is still an open research question which mutations are definitively drivers versus passengers. That being said, for your needs you might want to approach this problem from the perspective of more established tumor suppressors and oncogenes. Here is ...
written 21 months ago by Malachi Griffith17k
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Comment: C: Liftover Of Na12878 Coordinates Into Hg19 Coordinates
... Detailed post on tools for converting genome coordinates between builds: https://www.biostars.org/p/65558/ ...
written 2.1 years ago by Malachi Griffith17k
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Comment: C: Updating dbSNP rs ids from old SNP data
... Detailed post on tools for converting coordinates between genome builds: https://www.biostars.org/p/65558/ ...
written 2.1 years ago by Malachi Griffith17k
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Comment: C: Converting Genome Coordinates From One Genome Version To Another (Ucsc Liftover,
... I have updated the example, but it should be noted that the majority of these tools generically support all major builds for multiple species (not just human). When a new build comes out, the "chain" files that explain how to convert to/from that build are usually released soon after. ...
written 2.1 years ago by Malachi Griffith17k

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