User: Bioninbo

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Bioninbo0
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Posts by Bioninbo

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Comment: C: gTEX normalize counts by genotype
... Hi mbyvcm and thanks for the input! I checked the thread https://www.biostars.org/p/118739/ and I think I understand what you suggest. I want to explore the gTEX data, and in particular the expression of genes/alleles in different tissues and for different types of individuals. I thought that corr ...
written 5 days ago by Bioninbo0
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Answer: A: gTEX normalize counts by genotype
... Hi Cindy, Thanks for your answer! Let me clarify myself. What I suggest is to use the information of eQTL in a given tissue to normalize each sample individually. For instance, if variant V is an eQTL that increases the expression of gene G. Could we quantify the amount of increase in expressi ...
written 5 days ago by Bioninbo0
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gTEX normalize counts by genotype
... Hello, I want to analyze the gTEX dataset, but I am not interested in the impact of genotypes on phenotypes (RNA-Seq data). In the lastest release of the gTEX data, more than 170,000 cis eQTL have been detected. Therefore a large amount of variation can be accounted by genetic loci. I was wonde ...
genotype gtex eqtl written 8 days ago by Bioninbo0

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