User: rafi.zon

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rafi.zon10
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Posts by rafi.zon

<prev • 6 results • page 1 of 1 • next >
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Creating a 5 or 10-fold cross validation based on sequence similarity of proteins
... Hi there, As the post title states I am trying to find an approach to construct a 5 or 10 fold cross validation dataset, applied to all of the currently available human proteins in Swiss-Prot (20.421 proteins). Ideally, in each of the folds there should be the most similar proteins in terms of th ...
machine-learnng proteins cross-validation written 16 months ago by rafi.zon10 • updated 12 weeks ago by trent0
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Comment: C: Are the somatic mutations in TCGA filtered for germline mutations?
... Didn't know they have a paper for each dataset. Will have a look, thanks. ...
written 19 months ago by rafi.zon10
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Are the somatic mutations in TCGA filtered for germline mutations?
... Hi, I read from somewhere an answer [Question: How do I get germline mutation data from TCGA][1] that the germline mutations are filtered from the somatic mutations in the MAF of open access data in TCGA. Is this truly the case? Another possibility could be that the somatic mutations are detec ...
tcga mutations filtering written 19 months ago by rafi.zon10 • updated 19 months ago by markus.riester500
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Comment: C: Exploring cancer mutation data portals
... Thanks a lot for your elaborate answer, Malachi. Your answer gave me a better overview of the problem at hand. Let's hope with time and more research efforts we will understand the pathogenic pathways (as for the TS) much better, leading to more harmonization. ...
written 2.7 years ago by rafi.zon10
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Comment: C: Exploring cancer mutation data portals
... Malachi, Thanks again! I already searched many of the databases for cancer driving mutations for doing supervised learning. The Cancer Gene Census is something in the line of what I'm looking for. However, what it provides is a list of cancer genes and it doesn't differentiate the passenger and dri ...
written 2.7 years ago by rafi.zon10
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Answer: A: Exploring cancer mutation data portals
... That's an excellent list of the different available databases. I'm doing a research about driver mutations vs. passenger mutations and I'm not sure which database to use to get a list of driver mutations that are known to **cause** cancer and not just appear in cancer samples. Which databases or a ...
written 2.7 years ago by rafi.zon10

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