User: Lorenz Becker

gravatar for Lorenz Becker
Reputation:
20
Status:
New User
Location:
Manchester, UK
Last seen:
1 year ago
Joined:
1 year, 7 months ago
Email:
l************@postgrad.manchester.ac.uk

PhD student working on cardiac RNA-seq. R and Python enthusiast.

Posts by Lorenz Becker

<prev • 4 results • page 1 of 1 • next >
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Comment: C: Comparing sum of log2 fold changes between timepoints
... Yeah, thought so. For a bit more context, this is an early figure in the paper, and is supposed just to summarise how we see the transcriptome change over time (i.e. "are there more changes early in life"). On consultation with a biostatistician, we are likely to replace it with a density plot of lo ...
written 12 months ago by Lorenz Becker20
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Comparing sum of log2 fold changes between timepoints
... I have RNA-seq data for four time points (spaced unequally), A B C and D. I have done both a spline and a group model to look for overall changes over time and between timepoints. Is there a way of testing whether the amount of up- or downregulation is different between A/B and B/C or C/D (e.g. whe ...
rna-seq statistics written 12 months ago by Lorenz Becker20 • updated 12 months ago by RamRS24k
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Comment: C: Configuring sleuth for log2FC - What are the dangers?
... Thank you for the referral! ...
written 19 months ago by Lorenz Becker20
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Configuring sleuth for log2FC - What are the dangers?
... **(Detailed) Background:** I'm working with Prof. Love's kallisto/sleuth and DESeq2 libraries, on my PhD, where I run an RNA-seq timecourse experiment comprising 6-8 samples per timepoint over four (unevenly spaced) developmental timepoints. My current model is `~ batch + CutRIN + ns( ImputedAgeDa ...
sleuth rna-seq written 19 months ago by Lorenz Becker20

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