User: zepper

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zepper40
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Posts by zepper

<prev • 4 results • page 1 of 1 • next >
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Answer: A: R+Gviz: Fake AlignmentsTrack() to visualize Enhancer-Promoter connections
... Thanks to everybody, who read this post and tried to help. I could solve the problem now. I was unfamiliar with the data format of Gviz tracks, but it turned out that the underlying data can be manipulated just as a regular GRanges object. After I finally found out that a simple ranges(track_ ...
written 12 days ago by zepper40
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Comment: C: Is Biostar Killing The Bioinformatics Core?
... I think most of these quite general questions would also perfectly apply to any wet lab group, too I honestly don't see how that allows to draw the conclusion that bioinformatic core facilities are less in demand than before. Our university clinic doesn't have a bioinformatic core, but would certa ...
written 12 days ago by zepper40
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Answer: A: Drugs targeting Gene Fusions
... Hello Ron, I think this very much depends on your definition of druggable and the mode of action of the drug in question, so I would be careful to generalize here. Consider for example MLL-fusions, a well known oncogene in hematopoietic malignancies (nicely reviewed e.g. by Robert Slany PMID 269 ...
written 12 days ago by zepper40
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R+Gviz: Fake AlignmentsTrack() to visualize Enhancer-Promoter connections
... Hello Biostars-Community, I would need your kind suggestions regarding an issue with the Gviz package from Bioconductor. I am attempting plot Enhancer-Promoter connections and tried to (mis)use the AlignmentsTrack() function and the "sashimi" plots display type for it. Typically, alignment track ...
R genomicranges sashimi gviz written 12 days ago by zepper40

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