User: April

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April0
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Posts by April

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Comment: C: MutSig coverage table
... No problem. I added the synonymous mutations back and it worked. So make sure the input file includes both synonymous and nonsynonymous mutations. ...
written 5 days ago by April0
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Sciclone cluster all around y=x
... I am trying to use Sciclone to do clustering on my paired diagnostic and relapsed WES data. However, all the clusters in each patient are around line y=x. But I expect to see some clusters like the cluster 4, 5 in the example figure, which was only in the diagnostic or only in the relapsed sample. H ...
sciclone written 6 days ago by April0 • updated 6 days ago by RamRS26k
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Comment: A: How can i adjust the VAF values based on newly correctly estimated tumor purity
... Hi, how did you solve this problem? ...
written 4 months ago by April0
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how to analyze and summarize multiple whole-exome-sequencing studies
... Hi everyone, there are several similar whole-exome-sequencing studies published in the same disease. I would like to summarize them. However, i don't want to just describe or list what they found. I know we can do a meta-analysis to combine data from different studies. Is there any similar method to ...
next-gen written 8 months ago by April0
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Comment: A: MutSig coverage table
... Hi Sadiq I came across the same error. I am thinking that may because I used the non-synonymous mutations only. because according to the "mutation_type_dictionary_file", only silent and synonymous mutations are classified as "silent". thus in my data, there are no silent mutations. right now i'm try ...
written 11 months ago by April0

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