## User: discombobulated

Reputation:
10
Status:
New User
Location:
Last seen:
11 months, 2 weeks ago
Joined:
1 year ago
Email:
c********@gmail.com

#### Posts by discombobulated

<prev • 6 results • page 1 of 1 • next >
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... looking at your output, low has been coded as 1 (your outcome) and high as 0 (the reference). So you are correct that the hazard ratio is reported for Low - i.e HR of Low is 0.06. As the HR is less than 1, Low has a hazard reduction. While it is often reported as risk, technically this is not corre ...
written 11 months ago by discombobulated10
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... Hi. Yes you are correct but you need to be careful in how you explain it. Your hazard ratio is 0.05 (ie 0.05:1) but you reduce your hazard by a factor of 95% (ie your hazard ratio as such hasn't decreased). It is only a nuance but it changes the meaning. I suggest reporting the hazard ratio (HR = 0. ...
written 12 months ago by discombobulated10
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... In the interest of learning you can test your theory by implementing the --beta flag into your analysis. This will return the regression coefficients. plink --bfile mydata --logistic --beta ...
written 12 months ago by discombobulated10
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... Basically they use different methods for the calculation of the odds ratio - logistic uses the logistic regression model and assoc uses allele counts. Your differences aren't that large but the rarer the allele the greater the difference you may see. Have a read of Plink 1.07 manual - it is outlined ...
written 12 months ago by discombobulated10
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... Thanks [genomax][1]. I did as you suggested and contacted the developer. It is calculated using the formula developed by[ \[Marchini and Howie\]][2] in their 2010 Nature Review Genetics paper. [1]: https://www.biostars.org/u/18713/ [2]: https://www.nature.com/articles/nrg2796 ...
written 12 months ago by discombobulated10
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... Hi I am trying to find what exactly does the INFO score from the results of [Bolt LMM][1] measure (there is nothing in the user manual and google has come up empty). I am assuming that it refers to the imputation accuracy taken from the genotype probabilities but does anyone have a link or know wha ...
written 12 months ago by discombobulated10 • updated 12 months ago by Pierre Lindenbaum133k

#### Latest awards to discombobulated

Scholar 12 months ago, created an answer that has been accepted. For C: How is the Bolt LMM INFO Score calculated?

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