User: 2001linana
2001linana • 10
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Posts by 2001linana
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... Hi. I was reading an article with title "topology entropy of DNA sequences". So, in the abstract, it said, "...We compute its expected value and apply this definition to the intron and exon regions of the human genome to observe that as expected, the entropy of introns are significantly higher than ...
written 2 days ago by
2001linana • 10
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... The article is here: https://www.sciencedirect.com/science/article/pii/S0888754320303189 ...
written 2 days ago by
2001linana • 10
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... Hi. I was reading an article and encountered this. "The SNP mutations including nucleotide changes and the corresponding positions in a genome are called an SNP profile." I assume this talks about the nucleotide changes (during mutations) and the corresponding positions in a genome. The question is, ...
written 2 days ago by
2001linana • 10
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... I hope this is not a naive question. I was a bit curious about the meaning of genotyping. From wiki, I got the following. "Genotyping is the process of determining differences in the genetic make-up (genotype) of an individual by examining the individual's DNA sequence using biological assays and co ...
written 2 days ago by
2001linana • 10
• updated
2 days ago by
swbarnes2 ♦ 9.1k
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... 1: Why do we have the "same size datasets" requirement, as I did not see this from the formula definition.
2: So we can choose what we'd like the subsets to be in the definition then? What do you mean "the argument above about the subsets is valid only if the subsets somehow include all present and ...
written 2 days ago by
2001linana • 10
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... You mean it is not very precise, so it only applies to the situation when the sequences are relatively similar to each other, right? The set A and set B are not the genome sequences, but rather the variants detected in set A and set B respectively. In another article with title "genotyping coronavir ...
written 2 days ago by
2001linana • 10
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... I'm reading an article with title "characterizing sars cov 2 mutations in the united states" lately and got confused about this Jaccard distance. So, the article is trying to use the Jaccard distance to measure the similarity between SNP variants and compare the difference between the SNP variant pr ...
written 3 days ago by
2001linana • 10
• updated
2 days ago by
Mensur Dlakic • 7.1k
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... One of my coworker once told me that, some mutants tend to die out and some mutants tend to prosper. Does this have something to do with the stability of the protein it's involved with then? ...
written 3 days ago by
2001linana • 10
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... So do you mean that a mutation will almost always stabilize the structure of a protein? By the way, why is this not a bioinformatics question ? ...
written 3 days ago by
2001linana • 10
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... I was reading a sentence, saying "a positive folding stability change indicates that the mutation will stabilize the structure of the protein and vice versa." So what is exactly "a positive folding stability change" ? Any comments are greatly appreciated. ...
written 3 days ago by
2001linana • 10
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