User: 2001linana

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2001linana10
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Posts by 2001linana

<prev • 47 results • page 1 of 5 • next >
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is this a typo in this article?
... Hi. I was reading an article with title "topology entropy of DNA sequences". So, in the abstract, it said, "...We compute its expected value and apply this definition to the intron and exon regions of the human genome to observe that as expected, the entropy of introns are significantly higher than ...
sequence sequencing written 2 days ago by 2001linana10
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Comment: C: each strain has its own SNP (single nucleotide polymorphism) mutations in which
... The article is here: https://www.sciencedirect.com/science/article/pii/S0888754320303189 ...
written 2 days ago by 2001linana10
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each strain has its own SNP (single nucleotide polymorphism) mutations in which time frame?
... Hi. I was reading an article and encountered this. "The SNP mutations including nucleotide changes and the corresponding positions in a genome are called an SNP profile." I assume this talks about the nucleotide changes (during mutations) and the corresponding positions in a genome. The question is, ...
sequence sequencing written 2 days ago by 2001linana10
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difference between genotyping and sequencing ?
... I hope this is not a naive question. I was a bit curious about the meaning of genotyping. From wiki, I got the following. "Genotyping is the process of determining differences in the genetic make-up (genotype) of an individual by examining the individual's DNA sequence using biological assays and co ...
sequence sequencing written 2 days ago by 2001linana10 • updated 2 days ago by swbarnes29.1k
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Comment: C: how to understand this "Jaccard distance" ?
... 1: Why do we have the "same size datasets" requirement, as I did not see this from the formula definition. 2: So we can choose what we'd like the subsets to be in the definition then? What do you mean "the argument above about the subsets is valid only if the subsets somehow include all present and ...
written 2 days ago by 2001linana10
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Comment: C: how to understand this "Jaccard distance" ?
... You mean it is not very precise, so it only applies to the situation when the sequences are relatively similar to each other, right? The set A and set B are not the genome sequences, but rather the variants detected in set A and set B respectively. In another article with title "genotyping coronavir ...
written 2 days ago by 2001linana10
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how to understand this "Jaccard distance" ?
... I'm reading an article with title "characterizing sars cov 2 mutations in the united states" lately and got confused about this Jaccard distance. So, the article is trying to use the Jaccard distance to measure the similarity between SNP variants and compare the difference between the SNP variant pr ...
sequence sequencing written 3 days ago by 2001linana10 • updated 2 days ago by Mensur Dlakic7.1k
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Comment: C: what is exactly "protein folding energy"?
... One of my coworker once told me that, some mutants tend to die out and some mutants tend to prosper. Does this have something to do with the stability of the protein it's involved with then? ...
written 3 days ago by 2001linana10
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Comment: C: what is exactly "protein folding energy"?
... So do you mean that a mutation will almost always stabilize the structure of a protein? By the way, why is this not a bioinformatics question ? ...
written 3 days ago by 2001linana10
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what is exactly "protein folding energy"?
... I was reading a sentence, saying "a positive folding stability change indicates that the mutation will stabilize the structure of the protein and vice versa." So what is exactly "a positive folding stability change" ? Any comments are greatly appreciated. ...
sequence sequencing written 3 days ago by 2001linana10

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