User: Christophe Dessimoz
Christophe Dessimoz • 390
- Reputation:
- 390
- Status:
- Trusted
- Location:
- University College London
- Website:
- http://lab.dessimoz.org/
- Twitter:
- cdessimoz
- Scholar ID:
- Google Scholar Page
- Last seen:
- 2 months, 3 weeks ago
- Joined:
- 3 years, 7 months ago
- Email:
- c*********@ucl.ac.uk
Posts by Christophe Dessimoz
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2
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... Although OMA standalone and ESPRIT run within the same software, they have different purposes and for the moment we don't provide a unified pipeline between the two. This means that you have to take a two step process:
1. Run ESPRIT to identify likely split genes (which is what you appear to have ...
written 12 weeks ago by
Christophe Dessimoz • 390
4
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1
answer
143
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... Hi Natasha,
1. Smith-Waterman alignments are necessarily more sensitive than
blast alignments. The reason you might get more hits is likely due
to differences in length and minimum score thresholds. You can play
with these parameters in OMA Standalone (but as you hint, lowering
fa ...
written 12 weeks ago by
Christophe Dessimoz • 390
0
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1
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265
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... We recommend using protein sequences, because we have done much more benchmarking on this type of data. There are practical advantages too: public genomes exported from OMA, including precomputed all-against-all, are only available at for protein sequences. By contrast, the DNA-level comparison supp ...
written 5 months ago by
Christophe Dessimoz • 390
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1
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... No, OMA does not translate DNA into AA.
While it's true that Gonnet PAM matrices were defined on amino-acid, it's also possible to derive empirical scoring matrices from DNA in the same way. In OMA standalone, if the input data type is DNA, we use such matrices to perform alignment and evolutionary ...
written 5 months ago by
Christophe Dessimoz • 390
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... **Lecturer/Senior Lecturer in Computational Biology & Lecturer/Senior Lecturer in Human Genetics**
The [UCL Genetics Institute (UGI)][1] is an internationally leading centre for research and teaching in genetics and genomics. It is part of the Research Department of [Genetics, Evolution and Env ...
written 6 months ago by
Christophe Dessimoz • 390
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... Have you ever used the GO? Of course you have! Every bioinformatician worth their salt has on occasions been guilty of performing one GO enrichment analysis or ten. And in so doing, did you have the nagging feeling that you did not quite fully understand the ins and outs of what you were doing?
If ...
written 6 months ago by
Christophe Dessimoz • 390
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2
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290
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... The work chunks that have finished computing will be reused—it does not matter what job scheduler you used or if you even used one in the first place. These are the gzipped files in the Cache/AllAll folder.
However, if the SGE run was interrupted, there might be some chunks that are incomplete and ...
written 6 months ago by
Christophe Dessimoz • 390
0
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1
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284
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... If you don't want to run OMA standalone, you can download all HOGs from the current OMA release—the file ("Hierarchical Orthologous Groups") is linked from this page: http://omabrowser.org/oma/current/
To parse this file and retrieve HOGs defined at the various levels, I recommend that you use this ...
written 6 months ago by
Christophe Dessimoz • 390
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... Our lab has several open positions, and so do collaborators and colleagues across Switzerland, the UK, and Europe.
**Bioinformatic openings associated with our lab**
- [Two PhD positions in big data comparative genomics based at the University of Lausanne][1]
- [One 3-year postdoc position in ...
written 7 months ago by
Christophe Dessimoz • 390
1
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1
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508
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... It may be more straightforward to infer your orthologs using our software package OMA standalone (http://omabrowser.org), which takes your two fasta files as input and produces all pairwise relationships.
If you want to combine your two genomes with publicly available data, you can also export pre ...
written 8 months ago by
Christophe Dessimoz • 390
Latest awards to Christophe Dessimoz
Appreciated
6 months ago,
created a post with more than 5 votes.
For The Gene Ontology Handbook (open access)
Scholar
16 months ago,
created an answer that has been accepted.
For A: Details of OMA Running Process - OMA standalone
Popular Question
18 months ago,
created a question with more than 1,000 views.
For (Senior) Research Associate In Bioinformatics And Comparative Genomics At Ucl, London
Scholar
18 months ago,
created an answer that has been accepted.
For A: Details of OMA Running Process - OMA standalone
Teacher
18 months ago,
created an answer with at least 3 up-votes.
For A: Details of OMA Running Process - OMA standalone
Scholar
20 months ago,
created an answer that has been accepted.
For A: Details of OMA Running Process - OMA standalone
Teacher
20 months ago,
created an answer with at least 3 up-votes.
For A: Details of OMA Running Process - OMA standalone
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