Question

PAML method for estimation of dN/dS

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9.3 years ago

evo_genomics ▴ 60

I am estimating synonymous/non synonymous substitution rate (dN/dS) of gene in primate lineage. Which method of PAML is most appropriate for estimation of dN/dS ratio along each branch of primate lineage.

selection gene lineage • 3.0k views

ADD COMMENT • link updated 2.1 years ago by Ram 43k • written 9.3 years ago by evo_genomics ▴ 60

Ram · Answer 1 · 2015-01-26

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9.3 years ago

Brice Sarver ★ 3.8k

codeml branch or branch-site models.

ADD COMMENT • link updated 2.1 years ago by Ram 43k • written 9.3 years ago by Brice Sarver ★ 3.8k

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Thank you

ADD REPLY • link updated 2.1 years ago by Ram 43k • written 9.2 years ago by evo_genomics ▴ 60