Question: Segment Calling Algorithm For Mixed Density Array Cgh
2
gravatar for Ps376
8.0 years ago by
Ps37620
Ps37620 wrote:

Hi all,

I have a mixed density array CGH (highly densed regions interspersed with low density regoins). Is there a segmentation algorithm out there that works best with this kind of array? That is optimized to call segments (and possibly assign copy number states) for a mixed probe density array?

cnv • 1.5k views
ADD COMMENTlink written 8.0 years ago by Ps37620
1
gravatar for Sean Davis
8.0 years ago by
Sean Davis25k
National Institutes of Health, Bethesda, MD
Sean Davis25k wrote:

There are several, but I believe this was the first:

BioHMM: a heterogeneous hidden Markov model for segmenting array CGH data

ADD COMMENTlink written 8.0 years ago by Sean Davis25k

Hi,

Thanks so much for the suggestion! I am looking into BioHMM, and it definitely seems useful. You mention there are several such algorithms...would you happen to know any others specifically? Since I am working on new data, I wanted to be able to try different algorithms to see what works best for our dataset. Thanks again!!

ADD REPLYlink written 8.0 years ago by Ps37620
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 2922 users visited in the last hour