Entering edit mode
8.7 years ago
prabha
▴
10
What would be the right number of variant prediction tools to use in order to determine their deleteriousness? For example, if we use annovar there are 15 tools in the pipeline for variant annotation, so how many to use among them. And if we use more than one or all the tools, what should be the cutoff (number of tools to predict the variant to be deleterious out of total)? Kindly suggest the most effective tools to use for somatic and germ line variants and its reason.
