Contact residue map of mutated protein around active sites
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6.1 years ago
Saad Khan ▴ 400

Hi,

We did some exome sequencing analysis and we have identified some novel mutations that are damaging (according to SIFT predictions) In order to add some protein structure analysis to that work I need to generate contact map of the mutated residues and the active sites around that mutation. I intend to generate the figures which look somewhat like figure b & c in this figure http://www.nature.com/nature/journal/v462/n7274/fig_tab/nature08617_F3.html. I already have generated the structure pdb files using swiss-model. Since I don't have much experience with protein structure analysis I was wondering if somebody can give me pointers as to how I should generate a figure similar to the one given above using either chimera/pymol.

regards

pymol chimera active-site contact-map • 1.5k views
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