if i have two markers that are 100 Mb apart on the same chromosome, and i know that for my chromosome, centiMorgan to megaBase ratio is .9, then how many offspring in a generation can i expect to recombine between A and B?
since 1 centiMorgan is roughly 1 megaBase in this case, and 1 centiMorgan is 1% of the generation, then it would not make sense to say that 100% of the offspring would have recombined. The recombination frequency is bounded at 0.5.
so how can this be estimated? must i use haldane's function? what is a good way to think of this? thanks.